Evidence map›Paper›PMID 38819399›Full record

ArticleXenobiotica; the fate of foreign compounds in biological systems2024

Assessment of P-glycoprotein function using canine intestinal organoid-derived epithelial interfaces.

Itsuma Nagao, Meg Nakazawa, Yurika Tachibana, Minae Kawasaki, Yoko M Ambrosini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Xenobiotica; the fate of foreign compounds in biological systems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Canine duodenal organoids as a functional platform for intestinal CYP regulation and drug metabolism studies.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Itsuma NagaoDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Meg NakazawaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Yurika TachibanaDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Minae KawasakiDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Yoko M AmbrosiniDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.

Funding

Deciphering the Role of Gut Microbiome in Inflammatory Bowel Disease Using a Canine Patient-Specific Gut-on-a-ChipK01OD030515 · OD · WASHINGTON STATE UNIVERSITY · PI AMBROSINI, YOKO MIYAMOTO · 2021 to 2025
$513k
Deciphering the Pathogenesis of EHEC Infection and the Effects of Bacteria-Based Therapies Using Comparative Gut-on-a-ChipR21OD031903 · OD · WASHINGTON STATE UNIVERSITY · PI AMBROSINI, YOKO MIYAMOTO · 2022 to 2023
$419k
NIH HHS K01 OD030515NIH HHS R21 OD031903
6 · The paper itself

Abstract

P-glycoprotein (P-gp), a multidrug efflux pump encoded by the

Indexed as

ATP Binding Cassette Transporter, Subfamily B, Member 1DoxorubicinOrganoidsRhodamine 123AnimalsBiological TransportCyclosporinsDogsIntestinal MucosaATP Binding Cassette Transporter, Subfamily B, Member 1CyclosporinsDoxorubicinRhodamine 123valspodarcolonoidDogdrug transportintestinal organoidP-glycoprotein

Identifiers

PMID38819399
PMCPMC11325560

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.