Evidence map›Paper›PMID 38819384›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2024

S100A1's single cysteine is an indispensable redox switch for the protection against diastolic calcium waves in cardiomyocytes.

Andreas Seitz, Martin Busch, Jasmin Kroemer, Andrea Schneider, Stephanie Simon, Andreas Jungmann, Hugo A Katus, Patrick Most, Julia Ritterhoff

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andreas SeitzMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Martin BuschMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Jasmin KroemerMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Andrea SchneiderMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Stephanie SimonMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Andreas JungmannMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Hugo A KatusGerman Centre for Cardiovascular Research (DZHK), partner site Heidelberg/Mannheim, Heidelberg, Germany.
Patrick MostMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.
Julia RitterhoffMolecular and Translational Cardiology, Department of Internal Medicine III, Heidelberg University Hospital, Heidelberg, Germany.ORCID 0000-0002-3419-4830

Funding

Deutsches Zentrum für Herz-Kreislaufforschung (DZHK) 81X3500143Deutsches Zentrum für Herz-Kreislaufforschung (DZHK) 81Z0500101Klaus Tschira Stiftung (KTS) Informatics for Life consortium
6 · The paper itself

Abstract

The EF-hand calcium (Ca

Indexed as

Calcium SignalingCysteineMyocytes, CardiacOxidation-ReductionRyanodine Receptor Calcium Release ChannelS100 ProteinsAnimalsDiastoleGlutathioneMaleMiceMice, Inbred C57BLMyocardial ContractionProtein Processing, Post-TranslationalSarcoplasmic ReticulumCysteineGlutathioneryanodine receptor 2. mouseRyanodine Receptor Calcium Release ChannelS100A1 proteinS100 Proteinscalciumdiastolic calcium wavesintrinsically disordered proteinryanodine receptor 2S100A1

Identifiers

PMID38819384
PMCPMC11381028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.