Evidence map›Paper›PMID 38819382›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2024

Guidelines for in vivo models of developmental programming of cardiovascular disease risk.

Junie P Warrington, Helen E Collins, Sandra T Davidge, Jussara M do Carmo, Styliani Goulopoulou, Suttira Intapad, Analia S Loria, Jenny L Sones, Loren E Wold, Erin K Zinkhan and 1 more

Erratum issuedAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Junie P WarringtonDepartment of Neurology, University of Mississippi Medical Center, Jackson, Mississippi, United States.ORCID 0000-0001-5626-8872
Helen E CollinsDivision of Environmental Medicine, Department of Medicine, Center for Cardiometabolic Science, University of Louisville, Louisville, Kentucky, United States.ORCID 0000-0002-9302-6044
Sandra T DavidgeWomen and Children's Health Research Institute, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0002-5559-4905
Jussara M do CarmoDepartment of Physiology, University of Mississippi Medical Center, Jackson, Mississippi, United States.ORCID 0000-0003-0471-0512
Styliani GoulopoulouLawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University, Loma Linda, California, United States.ORCID 0000-0001-7636-8256
Suttira IntapadDepartment of Pharmacology, Tulane University, New Orleans, Louisiana, United States.
Analia S LoriaDepartment of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, Kentucky, United States.ORCID 0000-0002-9284-2146
Jenny L SonesEquine Reproduction Laboratory, Department of Clinical Sciences, Colorado State University College of Veterinary Medicine and Biomedical Sciences, Fort Collins, Colorado, United States.ORCID 0000-0002-5360-1243
Loren E WoldDivision of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States.ORCID 0000-0001-8155-0204
Erin K ZinkhanDepartment of Pediatrics, University of Utah and Intermountain Health, Salt Lake City, Utah, United States.ORCID 0000-0001-6085-6976
Barbara T AlexanderDepartment of Physiology, University of Mississippi Medical Center, Jackson, Mississippi, United States.ORCID 0000-0003-4992-2455

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 1993 to 2018
$39.4M
Tracking and Evaluation CoreU54GM115428 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI COMPRETTA, CAROLINE E. · 2016 to 2025
$38.2M
Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Pier Paolo Claudio, Babbette LaMarca · 2017 to 2026
$26.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
The role of maternal obesity-driven inflammation and adverse pregnancy outcomes in a mouse model of preeclampsiaP20GM135002 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Jacqueline M Stephens · 2020 to 2026
$18.4M
Pilot Projects ProgramP30GM149404 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI John E Hall · 2023 to 2026
$6.3M
Mechanisms of exposure-induced tissue functional and pathological changes in a mouse model of Alzheimer's DiseaseR01AG057046 · NIA · OHIO STATE UNIVERSITY · PI COMBS, COLIN K, DEL MONTE, FEDERICA · 2017 to 2021
$4.0M
Systematic identification of cardiotoxic e-cigarette flavorantsR01HL163818 · NHLBI · UNIVERSITY OF LOUISVILLE · PI Alex Perrow Carll, Matthew A Nystoriak · 2022 to 2026
$3.8M
Biosynthetic Pathways in Cardiac RemodelingR01HL147844 · NHLBI · UNIVERSITY OF LOUISVILLE · PI HILL, BRADFORD GUY, JONES, STEVEN P · 2019 to 2022
$3.0M
Preeclampsia and pre-clinical stages of maternal vascular dementiaR01HL146562 · NHLBI · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI GOULOPOULOU, STYLIANI · 2020 to 2024
$2.9M
Cardiac protective mechanisms of melanocortin system activationR01HL163076 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI Jussara M. Do Carmo, Alexandre Alves da Silva · 2023 to 2026
$2.3M
Effect of early life stress on obesity-induced hypertension in miceR01HL135158 · NHLBI · UNIVERSITY OF KENTUCKY · PI LORIA, ANALIA · 2018 to 2022
$2.1M
American Heart Association (AHA) 20YVNR35490079American Heart Association (AHA) 23SFRNPCS1067044CIHR FS154313HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) 1R01HL163076HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL146562-04S1HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) P01HL51971HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL135158HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL139348HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL143459HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL146562HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL147844HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL163003HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL163818HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R56HL159447HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01DK121411HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM104357HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM121334HHS | NIH | National Institute of General Medical Sciences (NIGMS) P20GM135002HHS | NIH | National Institute of General Medical Sciences (NIGMS) P30GM149404HHS | NIH | National Institute of General Medical Sciences (NIGMS) U54GM115428HHS | NIH | National Institute on Aging (NIA) R01AG057046Jewish Heritage Fund Excellence Faculty Support GrantNHLBI NIH HHS P01 HL051971NHLBI NIH HHS R01 HL135158NHLBI NIH HHS R01 HL139348NHLBI NIH HHS R01 HL143459NHLBI NIH HHS R01 HL146562NHLBI NIH HHS R01 HL147844NHLBI NIH HHS R01 HL163003NHLBI NIH HHS R01 HL163076NHLBI NIH HHS R01 HL163818NHLBI NIH HHS R56 HL159447NIA NIH HHS R01 AG057046NIDDK NIH HHS R01 DK121411NIGMS NIH HHS P20 GM104357NIGMS NIH HHS P20 GM121334NIGMS NIH HHS P20 GM135002NIGMS NIH HHS P30 GM149404NIGMS NIH HHS U54 GM115428
6 · The paper itself

Abstract

Research using animals depends on the generation of offspring for use in experiments or for the maintenance of animal colonies. Although not considered by all, several different factors preceding and during pregnancy, as well as during lactation, can program various characteristics in the offspring. Here, we present the most common models of developmental programming of cardiovascular outcomes, important considerations for study design, and provide guidelines for producing and reporting rigorous and reproducible cardiovascular studies in offspring exposed to normal conditions or developmental insult. These guidelines provide considerations for the selection of the appropriate animal model and factors that should be reported to increase rigor and reproducibility while ensuring transparent reporting of methods and results.

Indexed as

Cardiovascular DiseasesDisease Models, AnimalAnimalsFemaleFetal DevelopmentHeart Disease Risk FactorsHumansPregnancyPrenatal Exposure Delayed EffectsReproducibility of ResultsResearch DesignRisk Assessmentchronic diseasedevelopmental insultfetal growth restrictionoffspringpregnancy

Identifiers

PMID38819382
PMCPMC11380980

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.