Evidence map›Paper›PMID 38818921›Full record

ReviewCurrent drug discovery technologies2025

Phytophenols as Promoieties for Prodrug Design.

Bharat V Dhokchawle, Punit S Mishra, Renny J Daniel

Abstract readReview
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In one paragraph

Review in Current drug discovery technologies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Bharat V DhokchawleDepartment of Pharmaceutical Chemistry, St John Institute of Pharmacy and Research, Vevoor, Manor Road, Palghar (E), Dist-Palghar, 401404, Maharashtra, India.ORCID 0000-0002-1925-6183
Punit S MishraDepartment of Pharmaceutical Chemistry, St John Institute of Pharmacy and Research, Vevoor, Manor Road, Palghar (E), Dist-Palghar, 401404, Maharashtra, India.
Renny J DanielDepartment of Pharmaceutical Chemistry, St John Institute of Pharmacy and Research, Vevoor, Manor Road, Palghar (E), Dist-Palghar, 401404, Maharashtra, India.ORCID 0009-0001-7516-4478

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One lucrative method for overcoming challenges in drug discovery or for enhancing undesirable properties of already-approved medications is prodrug design. The goal of this review is to present researchers with a profile of naturally occurring Phytophenols as carriers that would be used for prodrug synthesis as well as their advantages. Phytophenols offer several advantages when used as promoieties as they also possess antioxidant and analgesic properties, they are obtained naturally and their safety profile is well established. Several phytophenols like menthol, thymol, eugenol, guaiacol, sesamol, vanillin, and umbelliferone are some of the phytophenols having several beneficial properties and are extensively employed in the field of food processing and medicine. In the current review, we have listed all types of promoieties that are used for prodrug synthesis and phytophenols are reviewed, which may help researchers to select phytophenols based on their need and suitability for drug candidates.

Indexed as

Drug DesignPhenolsPhytochemicalsProdrugsAnimalsAntioxidantsHumansAntioxidantsPhenolsPhytochemicalsProdrugsanti-oxidantgastric ulcerphytophenolsProdrugspromoietiestherapeutic agents.

Identifiers

PMID38818921

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.