Evidence map›Paper›PMID 38818751›Full record

ArticleAutophagy2024

RTN3L and CALCOCO1 function in parallel to maintain proteostasis in the endoplasmic reticulum.

Kamal Kumar, Ravi Chidambaram, Smriti Parashar, Susan Ferro-Novick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Autophagy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kamal KumarDepartment of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.
Ravi ChidambaramDepartment of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.
Smriti ParasharDepartment of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.
Susan Ferro-NovickDepartment of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA, USA.

Funding

The connection between ER-phagy, ER structure and hereditary spastic paraplegiasR01NS117440 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FERRO-NOVICK, SUSAN · 2020 to 2024
$2.4M
NINDS NIH HHS R01 NS117440
6 · The paper itself

Abstract

Reticulophagy is mediated by autophagy receptors that function in one of the two domains of the ER, tubules or flat sheets. Three different conserved mammalian receptors mediate autophagy in ER tubules: RTN3L, ATL3 and CALCOCO1. Previous studies have shown that RTN3L maintains proteostasis by targeting mutant aggregation-prone proteins for autophagy at distinct foci in ER tubules that we named ERPHS (

Indexed as

AutophagyEndoplasmic ReticulumMembrane ProteinsProteostasisCalcium-Binding ProteinsCarrier ProteinsGTP-Binding ProteinsGTP PhosphohydrolasesHeLa CellsHumansNerve Tissue ProteinsNogo ProteinsATL3 protein, humanCalcium-Binding ProteinsCarrier ProteinsGTP-Binding ProteinsGTP PhosphohydrolasesMembrane ProteinsNerve Tissue ProteinsNogo ProteinsRTN3 protein, humanRTN4 protein, humanAggregation-prone proteinsendoplasmic reticulumendoplasmic reticulum stressreticulophagy receptorsselective autophagy

Identifiers

PMID38818751
PMCPMC11346533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.