Evidence map›Paper›PMID 38818292›Full record

ReviewWorld journal of hepatology2024

Genetic screening of liver cancer: State of the art.

Milena Peruhova, Sonya Banova-Chakarova, Dimitrina Georgieva Miteva, Tsvetelina Velikova

Abstract readReview
In one paragraph

Review in World journal of hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Milena PeruhovaDepartment of Gastroenterology, University Hospital "Heart and Brain", Burgas 8000, Bulgaria.
Sonya Banova-ChakarovaDepartment of Gastroenterology, University Hospital "Heart and Brain", Burgas 8000, Bulgaria. sbanova86@gmail.com.
Dimitrina Georgieva MitevaDepartment of Genetics, Faculty of Biology, Sofia University" St. Kliment Ohridski, Sofia 1164, Bulgaria.
Tsvetelina VelikovaMedical Faculty, Sofia University St. Kliment Ohridski, Sofia 1407, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cancer, primarily hepatocellular carcinoma, remains a global health challenge with rising incidence and limited therapeutic options. Genetic factors play a pivotal role in the development and progression of liver cancer. This state-of-the-art paper provides a comprehensive review of the current landscape of genetic screening strategies for liver cancer. We discuss the genetic underpinnings of liver cancer, emphasizing the critical role of risk-associated genetic variants, somatic mutations, and epigenetic alterations. We also explore the intricate interplay between environmental factors and genetics, highlighting how genetic screening can aid in risk stratification and early detection

Indexed as

Circulating tumor DNAEpigenetic alterationsGenetic biomarkersGenetic screeningHepatocellular carcinomaLiver cancerNext-generation sequencingRisk-associated genetic variants

Identifiers

PMID38818292
PMCPMC11135278

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.