ReviewmLife2023
Gut microbiota research nexus: One Health relationship between human, animal, and environmental resistomes.
Review in mLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comprehensive in silico genomics analysis of global trends and host-specific emergence of aminoglycoside resistance in Staphylococcus aureus: a One-Health perspective.BMC microbiology · 2026Pooled it
- Pooled it
- Article
- Antibiotic resistance genes in companion animals and humans driven by the gut microbial communities: composition, distribution, and implications.BMC veterinary research · 2026Article
- Antibiotic Resistance Profiles of Commensal and Pathogenic Bacteria Isolated from Wild Boar Carcasses in Campania Region, Southern Italy.Antibiotics (Basel, Switzerland) · 2026Article
- Probiotic-based therapeutics for a One Health future: redefining antibiotic dependency to combat antimicrobial resistance.Frontiers in microbiology · 2026Article
- The resistome bridge between livestock and workers: novel frameworks for early detection and monitoring of antimicrobial resistance.Frontiers in public health · 2026Review
- Environmental exposures associated with the gut microbiome and resistome of pregnant women and children in Northwest Ecuador.Nature communications · 2025Article
- Dynamics of the gut microbiome and resistome in response to prophylactic antibiotic treatment in post-surgical giant pandas.Scientific reports · 2025Article
- Double-Edged Sword: Urbanization and Response of Amniote Gut Microbiome in the Anthropocene.Microorganisms · 2025Review
- Dynamic response of gut microbiota mediates the adaptation of Cipangopaludina chinensis to Pomacea canaliculata invasion.Microbiome · 2025Article
- Microbial Interconnections in One Health: A Critical Nexus Between Companion Animals and Human Microbiomes.Microorganisms · 2025Review
- Environmental Exposures and the Human Gut Resistome in Northwest Ecuador.medRxiv : the preprint server for health sciences · 2025Article
- Metagenomic Insights into the Diverse Antibiotic Resistome of Non-Migratory Corvidae Species on the Qinghai-Tibetan Plateau.Veterinary sciences · 2025Article
- Biosensor Technologies for Water Quality: Detection of Emerging Contaminants and Pathogens.Biosensors · 2025Review
- Global distribution of α/β hydrolase family macrolide esterases in Gram-positive bacteria.The ISME journal · 2025Article
- Geographic signatures in the oral resistome: a comparative metagenomic analysis of healthy individuals from Thailand and Norway.Journal of oral microbiology · 2025Article
- Characterization of mycobacteria isolated from the Brazilian Atlantic Forest: a public health and bioprospection perspective.Frontiers in microbiology · 2025Article
- Temporal signals in dairy cattle slurry and fertilized field soil resistomes and bacterial communities.Frontiers in microbiology · 2025Article
- Emerging contaminants: A One Health perspective.Innovation (Cambridge (Mass.)) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emergence and rapid spread of antimicrobial resistance is of global public health concern. The gut microbiota harboring diverse commensal and opportunistic bacteria that can acquire resistance via horizontal and vertical gene transfers is considered an important reservoir and sink of antibiotic resistance genes (ARGs). In this review, we describe the reservoirs of gut ARGs and their dynamics in both animals and humans, use the One Health perspective to track the transmission of ARG-containing bacteria between humans, animals, and the environment, and assess the impact of antimicrobial resistance on human health and socioeconomic development. The gut resistome can evolve in an environment subject to various selective pressures, including antibiotic administration and environmental and lifestyle factors (e.g., diet, age, gender, and living conditions), and interventions through probiotics. Strategies to reduce the abundance of clinically relevant antibiotic-resistant bacteria and their resistance determinants in various environmental niches are needed to ensure the mitigation of acquired antibiotic resistance. With the help of effective measures taken at the national, local, personal, and intestinal management, it will also result in preventing or minimizing the spread of infectious diseases. This review aims to improve our understanding of the correlations between intestinal microbiota and antimicrobial resistance and provide a basis for the development of management strategies to mitigate the antimicrobial resistance crisis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.