ArticleBMJ neurology open2024
Spontaneous spinal cord infarction: a systematic review.
Article in BMJ neurology open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Pediatric Spinal Cord Stroke: Clinical Presentation, MRI Features, and Suspected Mechanisms.Neurology. Clinical practice · 2026Article
- Routine Laboratory Parameters in the Differentiation of Spinal Cord Infarction and Seronegative Acute Myelitis: A Retrospective Study.Journal of clinical medicine · 2026Article
- C3 spinal cord infarction associated with cervical ossification of the posterior longitudinal ligament presenting as a stroke mimic: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study.Annals of clinical and translational neurology · 2026Observational
- Posterior Spinal Artery Infarction With Unilateral Lumbar Spinal Cord Lesion: A Challenge in Early Diagnosis.Journal of general and family medicine · 2026Article
- The owl's eyes sign in spinal cord infarction: A rare presentation at the conus.Radiology case reports · 2026Article
- Spinal Epidural Abscess Complicated by Compressive Myelopathy and Secondary Cord Ischemia: A Case Report.Case reports in surgery · 2026Article
- Spinal Cord Infarction Following Zoledronic Acid Administration in a Patient With Metastatic Prostate Cancer.Cureus · 2025Article
- Idiopathic Spinal Cord Infarction: A Case Report of an Unusual Diagnostic Dilemma and Therapeutic Challenge.Cureus · 2025Article
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- Spinal cord infarction after stenting for symptomatic severe stenosis of the basilar artery: a case description and literature analysis.Quantitative imaging in medicine and surgery · 2025Article
- Venous Congestive Myelopathy and Secondary Infarction: A Delayed Diagnosis of Spinal Dural Arteriovenous Fistula.Cureus · 2025Article
- Spinal Cord Infarction: Clinical and Neuroradiological Clues of a Rare Stroke Subtype.Journal of clinical medicine · 2025Review
- Spinal Cord Infarction as an Atypical Thromboembolic Complication of First-Diagnosed Atrial Fibrillation.International medical case reports journal · 2025Article
- Hypotension-Induced Transverse Spinal Cord Ischemia.European journal of case reports in internal medicine · 2025Article
- Long-term outcome and predictors of neurological recovery in cervical spinal cord injury: a population-based cohort study.Scientific reports · 2024Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and objectives: Spontaneous spinal cord infarction (SCInf) is a rare condition resulting in acute neurological impairment. Consensus on diagnostic criteria is lacking, which may present a challenge for the physician. This review aims to analyse the current literature on spontaneous SCInf, focusing on epidemiology, the diagnostic process, treatment strategies and neurological outcomes. Methods: The study was performed in accordance with a previously published protocol. PubMed, Web of Science and Embase were searched using the keywords 'spontaneous', 'spinal cord', 'infarction' and 'ischaemic'. The eligibility of studies was evaluated in two steps by multiple reviewers. Data from eligible studies were extracted and systematically analysed. Results: 440 patients from 33 studies were included in this systematic review. Analysis of vascular risk factors showed that hypertension was present in 40%, followed by smoking in 30%, dyslipidaemia in 29% and diabetes in 16%. The severity of symptoms at admission according to the American Spinal Injury Association (ASIA) Impairment Scale was score A 19%, score B14%, score C36% and score D32%. The mean follow-up period was 34.8 (±12.2) months. ASIA score at follow-up showed score A 11%, score B 3%, score C 16%, score D 67% and score E 2%. The overall mortality during the follow-up period was 5%. When used, MRI with diffusion-weighted imaging (DWI) supported the diagnosis in 81% of cases. At follow-up, 71% of the patients were able to walk with or without walking aids. Conclusion: The findings suggest a significant role for vascular risk factors in the pathophysiology of spontaneous SCInf. In the diagnostic workup, the use of DWI along with an MRI may help in confirming the diagnosis. The findings at follow-up suggest that neurological recovery is to be expected, with the majority of patients regaining ambulation. This systematic review highlights gaps in the literature and underscores the necessity for further research to establish diagnostic criteria and treatment guidelines.
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