ArticleJAMIA open2024
MENDS-on-FHIR: leveraging the OMOP common data model and FHIR standards for national chronic disease surveillance.
Article in JAMIA open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- A comparison of Fast Healthcare Interoperability Resources and Observational Medical Mutcomes Partnership electronic health record data within the All of Us Research Program.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Blocking the Reflection: Milestones and Hurdles for Digital Twins in Mental Health.Pharmacopsychiatry · 2026Review
- Toward bidirectional FHIR-OMOP CDM transformations using TermX to support the secondary use of real-world health data within a patient-centered digital health paradigm.Frontiers in medicine · 2026Article
- Semiautomatic mapping of a national drug terminology to standardised OMOP drug concepts using publicly available supplementary information.BMC medical research methodology · 2025Article
- SQL on FHIR - Tabular views of FHIR data using FHIRPath.NPJ digital medicine · 2025Article
- The role of open standards in catalysing knowledge transfer to deliver climate adaptive care.NPJ digital medicine · 2025Article
- Developing RxNorm Extension: A Step Toward Global Drug Data Harmonization in Observational Drug Research.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024Article
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13 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objectives: The Multi-State EHR-Based Network for Disease Surveillance (MENDS) is a population-based chronic disease surveillance distributed data network that uses institution-specific extraction-transformation-load (ETL) routines. MENDS-on-FHIR examined using Health Language Seven's Fast Healthcare Interoperability Resources (HL7 Materials and Methods: The input data source was a research data warehouse containing clinical and administrative data in OMOP CDM Version 5.3 format. OMOP-to-FHIR transformations, using a unique JavaScript Object Notation (JSON)-to-JSON transformation language called Whistle, created FHIR R4 V4.0.1/US Core IG V4.0.0 conformant resources that were stored in a local FHIR server. A REST-based Bulk FHIR $export request extracted FHIR resources to populate a local MENDS database. Results: Eleven OMOP tables were used to create 10 FHIR/US Core compliant resource types. A total of 1.13 trillion resources were extracted and inserted into the MENDS repository. A very low rate of non-compliant resources was observed. Discussion: OMOP-to-FHIR transformation results passed validation with less than a 1% non-compliance rate. These standards-compliant FHIR resources provided standardized data elements required by the MENDS surveillance use case. The Bulk FHIR application programming interface (API) enabled population-level data exchange using interoperable FHIR resources. The OMOP-to-FHIR transformation pipeline creates a FHIR interface for accessing OMOP data. Conclusion: MENDS-on-FHIR successfully replaced custom ETL with standards-based interoperable FHIR resources using Bulk FHIR. The OMOP-to-FHIR transformations provide an alternative mechanism for sharing OMOP data.
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