Evidence map›Paper›PMID 38818047›Full record

ArticleJACS Au2024

Biomimetic Vesicles with Designer Phospholipids Can Sense Environmental Redox Cues.

Huseyin Erguven, Liming Wang, Bryan Gutierrez, Andrew H Beaven, Alexander J Sodt, Enver Cagri Izgu

Abstract read
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huseyin ErguvenDepartment of Chemistry and Chemical Biology, Rutgers University, New Brunswick, New Jersey 08854, United States.
Liming WangDepartment of Chemistry and Chemical Biology, Rutgers University, New Brunswick, New Jersey 08854, United States.ORCID https://orcid.org/0000-0002-2269-5355
Bryan GutierrezDepartment of Chemistry and Chemical Biology, Rutgers University, New Brunswick, New Jersey 08854, United States.
Andrew H BeavenUnit on Membrane Chemical Physics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, United States.
Alexander J SodtUnit on Membrane Chemical Physics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, United States.ORCID https://orcid.org/0000-0002-5570-8212
Enver Cagri IzguDepartment of Chemistry and Chemical Biology, Rutgers University, New Brunswick, New Jersey 08854, United States.ORCID https://orcid.org/0000-0001-6673-3635

Funding

Molecular simulations of lipid curvature stress and its effect on transmembrane proteinsZIAHD008955 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI SODT, ALEXANDER · 2016 to 2025
$6.2M
6 · The paper itself

Abstract

Cell-like materials that sense environmental cues can serve as next-generation biosensors and help advance the understanding of intercellular communication. Currently, bottom-up engineering of protocell models from molecular building blocks remains a grand challenge chemists face. Herein, we describe giant unilamellar vesicles (GUVs) with biomimetic lipid membranes capable of sensing environmental redox cues. The GUVs employ activity-based sensing through designer phospholipids that are fluorescently activated in response to specific reductive (hydrogen sulfide) or oxidative (hydrogen peroxide) conditions. These synthetic phospholipids are derived from 1,2-dipalmitoyl-

Identifiers

PMID38818047
PMCPMC11134385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.