Evidence map›Paper›PMID 38818013›Full record

ArticleRSC advances2024

Synthesis of ciprofloxacin-linked 1,2,3-triazole conjugates as potent antibacterial agents using click chemistry: exploring their function as DNA gyrase inhibitors

Upendra Kumar Patel, Punit Tiwari, Ragini Tilak, Gaurav Joshi, Roshan Kumar, Alka Agarwal

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Upendra Kumar PatelDepartment of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University Varanasi UP-221005 India agarwal.dralka@gmail.com.ORCID https://orcid.org/0000-0001-7559-1923
Punit TiwariDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University Varanasi UP-221005 India.
Ragini TilakDepartment of Microbiology, Institute of Medical Sciences, Banaras Hindu University Varanasi UP-221005 India.
Gaurav JoshiDepartment of Pharmaceutical Sciences, Hemvati Nandan Bahuguna Garhwal University (Central University) Dist. Garhwal (Uttarakhand) Srinagar-246174 India.
Roshan KumarDepartment of Microbiology, Central University of Punjab Ghudda Bathinda-151401 India.
Alka AgarwalDepartment of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University Varanasi UP-221005 India agarwal.dralka@gmail.com.ORCID https://orcid.org/0000-0002-8136-6543

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antibacterial efficacy of some newly developed C-3 carboxylic group-containing ciprofloxacin-linked 1,2,3-triazole conjugates was studied. Twenty-one compounds from three different series of triazoles were synthesized using click chemistry and evaluated for their antibacterial activity against nine different pathogenic strains, including three Gram-positive strains,

Identifiers

PMID38818013
PMCPMC11138863

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.