Evidence map›Paper›PMID 38817779›Full record

ArticleJournal of surgical case reports2024

Platelet-rich plasma therapy for postoperative esophageal fistula in a pediatric patient.

Marco Di Mitri, Greta Chiastra, Edoardo Collautti, Simone D'Antonio, Marina Buzzi, Cristian Bisanti, Annalisa Di Carmine, Vincenzo Catania, Michele Libri, Tommaso Gargano and 1 more

Abstract readCase Reports
In one paragraph

Article in Journal of surgical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco Di MitriPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.ORCID https://orcid.org/0000-0003-0392-579X
Greta ChiastraPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Edoardo CollauttiPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Simone D'AntonioPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Marina BuzziEmilia Romagna Cord Blood Bank, Department of Pathology, IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna 40138, Italy.
Cristian BisantiPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Annalisa Di CarminePediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Vincenzo CataniaPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Michele LibriPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Tommaso GarganoPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.
Mario LimaPediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna 40138, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative management of esophagocutaneous fistulas in pediatric patients is challenging, often resulting in prolonged hospitalization and increased morbidity. Platelet-rich plasma (PRP) has emerged as a promising adjunctive treatment for such complications. We present the case of a 7-month-old infant who developed an esophago-cutaneous fistula following esophagocoloplasty for esophageal atresia type A. Despite initial conservative management, the fistula persisted, prompting the application of PRP gel derived from umbilical cord blood. After four applications of PRP, complete closure of the fistula was achieved, leading to both functional and aesthetic results. This case highlights the potential of PRP in managing refractory postoperative esophageal fistulas in pediatric patients and underscores the need for further research to optimize treatment protocols and validate its efficacy for this sort of complications.

Indexed as

colorectal surgerypediatric surgeryplastic surgeryupper GI surgeryurology

Identifiers

PMID38817779
PMCPMC11138110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.