Evidence map›Paper›PMID 38817573›Full record

ArticleChemical science2024

Discovery of a lagriamide polyketide by integrated genome mining, isotopic labeling, and untargeted metabolomics.

Claire H Fergusson, Julia Saulog, Bruno S Paulo, Darryl M Wilson, Dennis Y Liu, Nicholas J Morehouse, Samantha Waterworth, John Barkei, Christopher A Gray, Jason C Kwan and 2 more

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Claire H FergussonDepartment of Chemistry, Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada rliningt@sfu.ca.
Julia SaulogDepartment of Chemistry, Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada rliningt@sfu.ca.
Bruno S PauloDepartment of Pharmaceutical Sciences and Center for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago Chicago IL 60607 USA ase@uic.edu.
Darryl M WilsonDepartment of Chemistry, Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada rliningt@sfu.ca.
Dennis Y LiuDepartment of Chemistry, Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada rliningt@sfu.ca.
Nicholas J MorehouseDepartment of Biological Sciences, University of New Brunswick Saint John NB Canada.
Samantha WaterworthDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin Madison WI 53705 USA.
John BarkeiDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin Madison WI 53705 USA.
Christopher A GrayDepartment of Biological Sciences, University of New Brunswick Saint John NB Canada.
Jason C KwanDivision of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin Madison WI 53705 USA.ORCID https://orcid.org/0000-0001-9933-1536
Alessandra S EustaquioDepartment of Pharmaceutical Sciences and Center for Biomolecular Sciences, College of Pharmacy, University of Illinois at Chicago Chicago IL 60607 USA ase@uic.edu.ORCID https://orcid.org/0000-0002-7852-7844
Roger G LiningtonDepartment of Chemistry, Simon Fraser University 8888 University Drive Burnaby BC V5A 1S6 Canada rliningt@sfu.ca.ORCID https://orcid.org/0000-0003-1818-4971

Funding

Mining the cultured and uncultured biosphere for new drugsR35GM133776 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI KWAN, JASON CHRISTOPHER · 2019 to 2023
$2.1M
Development of a Bacterial Host for Natural Product Discovery and ProductionR01GM129344 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI EUSTAQUIO, ALESSANDRA S · 2020 to 2023
$1.5M
NIGMS NIH HHS R01 GM129344NIGMS NIH HHS R35 GM133776
6 · The paper itself

Abstract

Microorganisms from the order Burkholderiales have been the source of a number of important classes of natural products in recent years. For example, study of the beetle-associated symbiont

Identifiers

PMID38817573
PMCPMC11134395

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.