Evidence map›Paper›PMID 38817496›Full record

ArticleCureus2024

An Autopsy Case of Reversible Cerebral Vasoconstriction Syndrome After a Severe Acute Respiratory Syndrome Coronavirus 2 Vaccination.

Mai Shimura, Hirohisa Fujikawa, Masanobu Yazawa, Yuki Matsumoto, Mitsunori Yamada

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mai ShimuraDepartment of Medical Oncology, National Cancer Center Hospital East, Chiba, JPN.
Hirohisa FujikawaCenter for General Medicine Education, School of Medicine, Keio University, Tokyo, JPN.
Masanobu YazawaDepartment of Internal Medicine, Fujimi-Kogen Hospital, Fujimi-Kogen Medical Center, Nagano, JPN.
Yuki MatsumotoDepartment of Pathology, Shinshu University School of Medicine, Nagano, JPN.
Mitsunori YamadaDepartment of Brain Disease Research, Shinshu University School of Medicine, Nagano, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old man with chronic obstructive pulmonary disease received the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine. The following day, the patient developed a headache, followed by a tonic-clonic seizure and decreased consciousness. Magnetic resonance imaging of the head revealed no signs of stroke but multiple vasoconstrictions. Despite antiepileptic therapy, the seizure persisted, and the patient died 40 hours after vaccination. An autopsy revealed multiple brain ischemia without any vascular lesions, suggesting reversible cerebral vasoconstriction syndrome (RCVS). In this case, RCVS was diagnosed radiographically and pathologically. Our case suggests that RCVS could be a cause of headache and epilepsy following the SARS-CoV-2 mRNA vaccination.

Indexed as

autopsycovid-19epilepsyheadachercvssars-cov-2 vaccination

Identifiers

PMID38817496
PMCPMC11136619

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.