Evidence map›Paper›PMID 38817278›Full record

ArticleWorld journal of gastrointestinal surgery2024

Effects of oral probiotics on inflammation and intestinal function in adult patients after appendectomy: Randomized controlled trial.

Ke Lan, Ke-Rui Zeng, Fu-Rui Zhong, Sheng-Jin Tu, Jin-Long Luo, Shi-Long Shu, Xue-Feng Peng, Hua Yang, Kai Lu

Abstract read
In one paragraph

Article in World journal of gastrointestinal surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ke LanDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Ke-Rui ZengDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Fu-Rui ZhongDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Sheng-Jin TuDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Jin-Long LuoDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Shi-Long ShuDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Xue-Feng PengDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Hua YangDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China.
Kai LuDepartment of General Surgery, Zigong Fourth People's Hospital, Zigong 643000, Sichuan Province, China. 597768288@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAppendectomy is an acute abdominal surgery that is often accompanied by severe abdominal inflammation. Oral probiotics are one of the postoperative treatments for rapid rehabilitation. However, there is a lack of prospective studies on this topic after appendectomy.

aimTo investigate whether the postoperative probiotics can modulate the inflammatory response and restore intestinal function in patients following appendectomy.

methodsThis was a prospective, randomized trial. A total of 60 emergency patients were randomly divided into a control group (

resultsA total of 60 participants were included. Compared with those in the control group, the C-reactive protein (CRP), interleukin 6 and procalcitonin (PCT) levels were significantly lower in the probiotic group at 2 d after surgery (

conclusionPostoperative oral administration of probiotics may modulate the gut microbiota, benefit the recovery of the early inflammatory response, and subsequently enhance recovery after appendectomy.

Indexed as

AppendectomyEnhanced recovery after surgeryGut microbiotaInflammatory markersIntestinal functionPostsurgical infectionsProbiotics

Identifiers

PMID38817278
PMCPMC11135319

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.