Evidence map›Paper›PMID 38817151›Full record

ArticleBiochemistry2024

Catalytic Activity of the Archetype from Group 4 of the FTR-like Ferredoxin:Thioredoxin Reductase Family Is Regulated by Unique

Divya Prakash, Jin Xiong, Shikha S Chauhan, Karim A Walters, Hannah Kruse, Neela Yennawar, John H Golbeck, Yisong Guo, James G Ferry

Abstract read
In one paragraph

Article in Biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Divya PrakashSchool of Chemical and Biomolecular Sciences, Southern Illinois University-Carbondale, Carbondale, Illinois 62901, United States.ORCID 0000-0003-0080-2583
Jin XiongDepartment of Chemistry, The Carnegie Mellon University, Pittsburgh,, Pennsylvania 15213, United States.ORCID 0000-0001-7443-0554
Shikha S ChauhanSchool of Chemical and Biomolecular Sciences, Southern Illinois University-Carbondale, Carbondale, Illinois 62901, United States.
Karim A WaltersDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Hannah KruseSchool of Chemical and Biomolecular Sciences, Southern Illinois University-Carbondale, Carbondale, Illinois 62901, United States.
Neela YennawarThe Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.ORCID 0000-0001-7278-659X
John H GolbeckDepartment of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Yisong GuoDepartment of Chemistry, The Carnegie Mellon University, Pittsburgh,, Pennsylvania 15213, United States.ORCID 0000-0002-4132-3565
James G FerryDepartment of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.

Funding

Elucidate Mechanisms of Quinolone Alkaloid Biosynthesis via Iron(II)/2-Oxoglutarate Dependent Enzymes: Diverse, but Controlled ReactivityR01GM125924 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI Yisong Guo · 2018 to 2026
$3.3M
X-ray instrumentation upgrade for single crystal diffraction and solution small angle scatteringS10OD028589 · OD · PENNSYLVANIA STATE UNIVERSITY, THE · PI YENNAWAR, NEELA H. · 2020 to 2020
$600k
NIGMS NIH HHS R01 GM125924NIH HHS S10 OD028589
6 · The paper itself

Abstract

Thioredoxin reductases (TrxR) activate thioredoxins (Trx) that regulate the activity of diverse target proteins essential to prokaryotic and eukaryotic life. However, very little is understood of TrxR/Trx systems and redox control in methanogenic microbes from the domain

Indexed as

Iron-Sulfur ProteinsArchaeal ProteinsElectron Spin Resonance SpectroscopyFerredoxinsMethanosarcinaModels, MolecularOxidation-ReductionOxidoreductasesThioredoxin-Disulfide ReductaseThioredoxinsArchaeal ProteinsFerredoxinsferredoxin-thioredoxin reductaseIron-Sulfur ProteinsOxidoreductasesThioredoxin-Disulfide ReductaseThioredoxins

Identifiers

PMID38817151
PMCPMC11234629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.