Evidence map›Paper›PMID 38817081›Full record

ArticleOrthodontics & craniofacial research2024

Impact of protraction or orthognathic surgery for class III malocclusion on longitudinal quality of life in patients with cleft lip and palate.

Bocheng Gu, Alexis L Johns, Lamia Binhuwaishel, Amarjit Dass, Barbara Sheller, Hitesh P Kapadia, Stephen L-K Yen

Abstract read
In one paragraph

Article in Orthodontics & craniofacial research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Positive Longitudinal Caregiver Behavioral Ratings and Self-Reported Quality of Life in Youth With Cleft Lip and Palate in Treatment for Class III Malocclusion.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bocheng GuDepartment of Pharmaceutical and Health Economics, School of Pharmacy, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0009-0004-6618-732X
Alexis L JohnsDivision of Plastic and Maxillofacial Surgery, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Lamia BinhuwaishelDivision of Dentistry, Department of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Amarjit DassDivision of Dentistry, Department of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Barbara ShellerDepartment of Dentistry, Seattle Children's Hospital and School of Dentistry, University of Washington, Seattle, Washington, USA.
Hitesh P KapadiaDepartment of Dentistry, Seattle Children's Hospital and School of Dentistry, University of Washington, Seattle, Washington, USA.
Stephen L-K YenDivision of Dentistry, Department of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Funding

CLINICAL EFFECTIVENESS OF LATE MAXILLARY PROTRACTION FOR CLEFT LIP AND PALATEU01DE022937 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI YEN, STEPHEN L-K · 2013 to 2017
$3.4M
NIDCR NIH HHS U01 DE022937
6 · The paper itself

Abstract

objectivesThis study assessed overall quality of life (QoL) over time in youth with cleft lip and palate (CLP) undergoing maxillary protraction treatment or orthognathic surgery for class III malocclusion to identify any differences in QoL based on treatment group and outcome success. MATERIALS AND

methodsA prospective longitudinal cohort study was conducted in two pediatric hospitals. The Short Form Health Survey (SF-12) measured physical and mental QoL prior to treatment, at maximal correction, at treatment completion, and at 1-year post treatment. Analyses included one-sample, two-sample, and paired t-tests and analyses of variance and covariance.

resultsParticipants (N = 91) either completed protraction (n = 53) at age 11-14 or surgery (n = 38) at age 16-21. Participants were mostly Latinx (67%) males (55%) born with unilateral CLP (81%) and there were no demographic differences between the two groups other than age. The total sample's QoL was in the average range and significantly higher than national norms. No significant differences were found in QoL-based outcome success; however, the protraction group showed a gradual physical QoL improvement over time, while the surgery group experienced a temporary drop in physical QoL postoperatively. At treatment completion, higher physical QoL was associated with higher socioeconomic status. At a year post treatment, mental QoL was significantly higher for males.

conclusionBoth protraction and surgery appear to be acceptable treatment options in terms of overall QoL for youth with CLP. While treatment success did not impact QoL, there were some differences in physical QoL coinciding with the treatment phase as well as individual factors.

Indexed as

Cleft LipCleft PalateMalocclusion, Angle Class IIIOrthognathic Surgical ProceduresQuality of LifeAdolescentChildExtraoral Traction AppliancesFemaleHumansLongitudinal StudiesMaleProspective StudiesTreatment OutcomeYoung Adultclass III malocclusioncleft lip and palatemaxillary protractionorthognathic surgeryquality of life

Identifiers

PMID38817081
PMCPMC13322207

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.