Evidence map›Paper›PMID 38817012›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2024

Patterns of sub-optimal change following CBT for childhood anxiety.

Lizel-Antoinette Bertie, Kristian Arendt, Jonathan R I Coleman, Peter Cooper, Cathy Creswell, Thalia C Eley, Catharina Hartman, Einar R Heiervang, Tina In-Albon, Karen Krause and 12 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Lizel-Antoinette BertieSchool of Psychology, UNSW, Sydney, NSW, Australia.ORCID 0000-0002-8327-9515
Kristian ArendtDepartment of Psychology, University of Aarhus, Aarhus, Denmark.ORCID 0000-0002-4501-6028
Jonathan R I ColemanSocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, & King's College London, London, UK.ORCID 0000-0002-6759-0944
Peter CooperSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Cathy CreswellSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.ORCID 0000-0003-1889-0956
Thalia C EleySocial, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, & King's College London, London, UK.ORCID 0000-0001-6458-0700
Catharina HartmanDepartment of Psychiatry, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Einar R HeiervangDepartment of Clinical Medicine, Faculty of Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0002-8871-1098
Tina In-AlbonClinical Child and Adolescent Psychology and Psychotherapy, Department of Psychology, University of Koblenz-Landau, Landau, Germany.ORCID 0000-0002-2070-8458
Karen KrauseMental Health Research and Treatment Center, Ruhr-Universtät Bochum, Bochum, Germany.
Kathryn J LesterSchool of Psychology, University of Sussex, Brighton, UK.ORCID 0000-0002-0853-2664
Carla E MarinYale University, Child Study Center, New Haven, CT, USA.ORCID 0000-0002-6287-0111
Maaike NautaDepartment of Psychiatry, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.ORCID 0000-0001-7694-1382
Ronald M RapeeDepartment of Psychological Sciences, Centre for Emotional Health, Macquarie University, Sydney, NSW, Australia.ORCID 0000-0002-1724-1076
Silvia SchneiderMental Health Research and Treatment Center, Ruhr-Universtät Bochum, Bochum, Germany.ORCID 0000-0003-0698-8411
Carolyn SchnieringDepartment of Psychological Sciences, Centre for Emotional Health, Macquarie University, Sydney, NSW, Australia.ORCID 0000-0003-0194-0515
Wendy K SilvermanYale University, Child Study Center, New Haven, CT, USA.ORCID 0000-0003-4415-4098
Mikael ThastumDepartment of Psychology, University of Aarhus, Aarhus, Denmark.ORCID 0000-0001-8582-5682
Kerstin ThirlwallSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.
Polly WaiteSchool of Psychology and Clinical Language Sciences, University of Reading, Reading, UK.ORCID 0000-0002-1967-8028
Gro Janne WergelandDepartment of Clinical Medicine, Faculty of Medicine, University of Bergen, Bergen, Norway.ORCID 0000-0003-0913-5473
Jennifer L HudsonSchool of Psychology, UNSW, Sydney, NSW, Australia.ORCID 0000-0001-5778-2670

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Parent Mediation of Child Anxiety CBT OutcomeR01MH079943 · NIMH · FLORIDA INTERNATIONAL UNIVERSITY · PI PETTIT, JEREMY W · 2008 to 2012
$3.0M
Australian Research Council DP0878609Edith og Godtfred Kirk Christiansens Fond 21- 5675Medical Research Council 09-800-17Medical Research Council G0601874Medical Research Council G0802326Medical Research Council G0802821Medical Research Council G0901874/1Medical Research Council G1002011National Health and Medical Research Council 1027556National Health and Medical Research Council 382008National Health and Medical Research Council 488505National Institute for Health Research PB-PG-0107-12042National Institute for Health Research PB-PG-0110-21190NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH079943NIMH NIH HHS R01MH079943Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 105314-116517TrygFonden 7-10-1391Western Norway Regional Health Authority 911253Western Norway Regional Health Authority 911366
6 · The paper itself

Abstract

backgroundChildren and adolescents demonstrate diverse patterns of symptom change and disorder remission following cognitive behavioural therapy (CBT) for anxiety disorders. To better understand children who respond sub-optimally to CBT, this study investigated youths (N = 1,483) who continued to meet criteria for one or more clinical anxiety diagnosis immediately following treatment or at any point during the 12 months following treatment.

methodsData were collected from 10 clinical sites with assessments at pre-and post-treatment and at least once more at 3, 6 or 12-month follow-up. Participants were assigned to one of three groups based on diagnostic status for youths who: (a) retained an anxiety diagnosis from post to end point (minimal responders); (b) remitted anxiety diagnoses at post but relapsed by end point (relapsed responders); and (c) retained a diagnosis at post but remitted to be diagnosis free at end point (delayed responders). Growth curve models assessed patterns of change over time for the three groups and examined predictors associated with these patterns including demographic, clinical and parental factors, as well as treatment factors.

resultsHigher primary disorder severity, being older, having a greater number of anxiety disorders, having social anxiety disorder, as well as higher maternal psychopathology differentiated the minimal responders from the delayed and relapsed responders at the baseline. Results from the growth curve models showed that severity of the primary disorder and treatment modality differentiated patterns of linear change only. Higher severity was associated with significantly less improvement over time for the minimal and relapsed response groups, as was receiving group CBT, when compared to the delayed response group.

conclusionsSub-optimal response patterns can be partially differentiated using variables assessed at pre-treatment. Increased understanding of different patterns of change following treatment may provide direction for clinical decision-making and for tailoring treatments to specific groups of clinically anxious youth. Future research may benefit from assessing progress during treatment to detect emerging response patterns earlier.

Indexed as

Anxiety DisordersCognitive Behavioral TherapyAdolescentChildFemaleFollow-Up StudiesHumansMaleRecurrenceTreatment OutcomeAnxietychildhoodcognitive behavioural therapyresponse patternssub‐optimal response

Identifiers

PMID38817012
PMCPMC11563922

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.