Evidence map›Paper›PMID 38816943›Full record

Observational studyClinical and experimental dental research2024

The relationship between oral frailty and oral dysbiosis among hospitalized patients aged older than 50 years.

Yen-Chin Chen, En-Ni Ku, Pei-Fang Tsai, Che-Wei Lin, Nai-Ying Ko, Shun-Te Huang, Jiun-Ling Wang, Yi-Ching Yang

Abstract readObservational Study
In one paragraph

Observational study in Clinical and experimental dental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yen-Chin ChenCollege of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.ORCID 0000-0001-7353-3383
En-Ni KuDepartment of Nursing, Linkou Chang Gung Memorial Hospital, Taipei, Taiwan.
Pei-Fang TsaiDepartment of Pathology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Che-Wei LinDepartment of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan, Taiwan.
Nai-Ying KoDepartment of Nursing, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Shun-Te HuangDivision of Pediatric Dentistry and Special Care Dentistry, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Jiun-Ling WangDepartment of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Yi-Ching YangDepartment of Family Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Funding

Ministry of Science and Technology MOST 110-2314-B-006-025National Cheng Kung University Hospital NCKUH-11301003National Health Research Institutes NHRI-13A1-CG-CO-04-2225-1National Science and Technology Council NSTC112-2314-B-006-022-MY3
6 · The paper itself

Abstract

objectiveThis study aimed to clarify the relationship between oral frailty and oral dysbiosis among hospitalized patients aged ≥ 50 years.

methodsA prospective observational study was conducted. Number of teeth, masticatory ability, articulatory oral motor skill, tongue pressure, swallowing pressure, and choking were used to assess oral frailty. Saliva samples were collected from the oral cavity for bacterial culture.

resultsA total 103 in patients enrolled and 53.4% suffered from oral frailty. Oral frailty was found to have a 3.07-fold correlation with the presence of Enterobacterales in the oral cavity (p = 0.037), especially in poor articulatory oral motor skill, which showed at greater risk of Enterobacterales isolated from the oral cavity by 5.58-fold (p = 0.01).

conclusionHalf of hospitalized patients was found to have oral frailty that was related to more Enterobacterales in the oral cavity. This evidence suggests that the enhancement of articulatory oral motor skills may serve as a potential strategy for mitigating the presence of Enterobacterales within the oral cavity.

Indexed as

DysbiosisHospitalizationMouthSalivaAgedAged, 80 and overEnterobacteriaceaeFemaleFrailtyHumansMaleMasticationMiddle AgedProspective Studieshospitalized patientsmiddle‐age and older adults careoral dysbiosisoral frailty

Identifiers

PMID38816943
PMCPMC11139674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.