Evidence map›Paper›PMID 38816758›Full record

ArticleJournal of biomedical semantics2024

Explanatory argumentation in natural language for correct and incorrect medical diagnoses.

Benjamin Molinet, Santiago Marro, Elena Cabrio, Serena Villata

Abstract read
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Article in Journal of biomedical semantics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Benjamin MolinetUniversité Côte d'Azur, CNRS, Inria, I3S, Rte des Lucioles, Sophia Antipolis, 06900, Alpes-Maritimes, France. benjamin.molinet@univ-cotedazur.fr.
Santiago MarroUniversité Côte d'Azur, CNRS, Inria, I3S, Rte des Lucioles, Sophia Antipolis, 06900, Alpes-Maritimes, France.
Elena CabrioUniversité Côte d'Azur, CNRS, Inria, I3S, Rte des Lucioles, Sophia Antipolis, 06900, Alpes-Maritimes, France.
Serena VillataUniversité Côte d'Azur, CNRS, Inria, I3S, Rte des Lucioles, Sophia Antipolis, 06900, Alpes-Maritimes, France.

Funding

3IA Côte d'Azur ANR-19-P3IA-0002CHIST-ERA XAI Project-ANR-21-CHR4-0002
6 · The paper itself

Abstract

backgroundA huge amount of research is carried out nowadays in Artificial Intelligence to propose automated ways to analyse medical data with the aim to support doctors in delivering medical diagnoses. However, a main issue of these approaches is the lack of transparency and interpretability of the achieved results, making it hard to employ such methods for educational purposes. It is therefore necessary to develop new frameworks to enhance explainability in these solutions.

resultsIn this paper, we present a novel full pipeline to generate automatically natural language explanations for medical diagnoses. The proposed solution starts from a clinical case description associated with a list of correct and incorrect diagnoses and, through the extraction of the relevant symptoms and findings, enriches the information contained in the description with verified medical knowledge from an ontology. Finally, the system returns a pattern-based explanation in natural language which elucidates why the correct (incorrect) diagnosis is the correct (incorrect) one. The main contribution of the paper is twofold: first, we propose two novel linguistic resources for the medical domain (i.e, a dataset of 314 clinical cases annotated with the medical entities from UMLS, and a database of biological boundaries for common findings), and second, a full Information Extraction pipeline to extract symptoms and findings from the clinical cases and match them with the terms in a medical ontology and to the biological boundaries. An extensive evaluation of the proposed approach shows the our method outperforms comparable approaches.

conclusionsOur goal is to offer AI-assisted educational support framework to form clinical residents to formulate sound and exhaustive explanations for their diagnoses to patients.

Indexed as

Natural Language ProcessingArtificial IntelligenceDiagnosisDiagnostic ErrorsHumansUnified Medical Language SystemAI in medicineArgument-based natural language explanationsHealthcareInformation extractionNatural language processing

Identifiers

PMID38816758
PMCPMC11138001

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.