Evidence map›Paper›PMID 38816514›Full record

ArticleEMBO reports2024

Targeting ATP2B1 impairs PI3K/Akt/FOXO signaling and reduces SARS-COV-2 infection and replication.

Pasqualino de Antonellis, Veronica Ferrucci, Marco Miceli, Francesca Bibbo, Fatemeh Asadzadeh, Francesca Gorini, Alessia Mattivi, Angelo Boccia, Roberta Russo, Immacolata Andolfo and 16 more

Abstract read
In one paragraph

Article in EMBO reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. ATP2B1 expression identifies human hematopoietic stem cells with superior repopulation and self-renewal.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Pasqualino de Antonellis *CEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0001-8551-9431
Veronica Ferrucci *CEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0002-2019-6501
Marco MiceliCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Francesca BibboCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0002-2894-6629
Fatemeh AsadzadehCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Francesca GoriniDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), 'Federico II' University of Naples, Naples, 80131, Italy.ORCID 0000-0002-9762-4172
Alessia MattiviArmenise-Harvard Laboratory of Cell Division, Department of Cellular Computational and Integrative Biology-CIBIO, University of Trento, Trento, Italy.
Angelo BocciaCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Roberta RussoCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Immacolata AndolfoCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0003-0493-812X
Vito Alessandro LasorsaCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0002-9552-7192
Sueva CantalupoCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Giovanna FuscoIstituto Zooprofilattico Sperimentale del Mezzogiorno, Naples, 80055, Italy.ORCID 0000-0003-3139-7672
Maurizio ViscardiIstituto Zooprofilattico Sperimentale del Mezzogiorno, Naples, 80055, Italy.
Sergio BrandiIstituto Zooprofilattico Sperimentale del Mezzogiorno, Naples, 80055, Italy.ORCID 0000-0001-8345-7564
Pellegrino CerinoIstituto Zooprofilattico Sperimentale del Mezzogiorno, Naples, 80055, Italy.
Vittoria MonacoCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0002-7459-8733
Dong-Rac ChoiDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.
Jae-Ho CheongDepartment of Surgery, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-1703-1781
Achille IolasconCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Stefano AmenteDipartimento di Medicina Molecolare e Biotecnologie Mediche (DMMBM), 'Federico II' University of Naples, Naples, 80131, Italy.ORCID 0000-0003-0612-6096
Maria MontiCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.ORCID 0000-0002-7775-7154
Luca L FavaArmenise-Harvard Laboratory of Cell Division, Department of Cellular Computational and Integrative Biology-CIBIO, University of Trento, Trento, Italy.ORCID 0000-0002-6741-1723
Mario CapassoCEINGE Biotecnologie Avanzate, Naples, 80145, Italy.
Hong-Yeoul KimElysiumbio Inc., #2007, Samsung Cheil B/D, 309, Teheran-ro, Gangnam-gu, Seoul, 06151, Korea.
Massimo ZolloCEINGE Biotecnologie Avanzate, Naples, 80145, Italy. massimo.zollo@unina.it.ORCID 0000-0002-0970-7243

Funding

Fondazione AIRC per la ricerca sul cancro ETS (AIRC) Grant IG no. 22129Ministero dell'Istruzione, dell'Università e della Ricerca (MIUR) 2017FNZRN3Ministry of Science and ICT, South Korea (MSIT) NRF 2018R1A5A2025079Regione Campania D64I200003800
6 · The paper itself

Abstract

ATP2B1 is a known regulator of calcium (Ca

Indexed as

CalciumCOVID-19Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSARS-CoV-2Signal TransductionVirus ReplicationAnimalsCalcium-Transporting ATPasesChlorocebus aethiopsCOVID-19 Drug TreatmentFemaleForkhead Box Protein O3HumansMaleVero CellsCalciumCalcium-Transporting ATPasesForkhead Box Protein O3FOXO3 protein, humanPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktATP2B1Ca2+PI3K/Akt/FOXOSARS-CoV-2Transcription

Identifiers

PMID38816514
PMCPMC11239940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.