Evidence map›Paper›PMID 38816444›Full record

ArticleScientific reports2024

Identification of small molecular inhibitors of SIRT3 by computational and biochemical approaches a potential target of breast cancer.

Atta Ullah, Najeeb Ur Rehman, Waseem Ul Islam, Faizullah Khan, Muhammad Waqas, Sobia Ahsan Halim, Afnan Jan, Abdullatif Bin Muhsinah, Ajmal Khan, Ahmed Al-Harrasi

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In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Atta Ullah *Natural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman.
Najeeb Ur Rehman *Natural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman.
Waseem Ul IslamDepartment of Pharmacy, University of Swabi, Khyber Pakhtunkhwa, Pakistan.
Faizullah KhanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman.
Muhammad WaqasNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman.
Sobia Ahsan HalimNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman. sobia_halim@unizwa.edu.om.
Afnan JanDepartment of Biochemistry, Faculty of Medicine, Umm Al-Qura University, Mecca, Kingdom of Saudi Arabia.
Abdullatif Bin MuhsinahDepartment of Pharmacognosy, College of Pharmacy, King Khalid University, 61441, Abha, Saudi Arabia.
Ajmal KhanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman. ajmalkhan@unizwa.edu.om.
Ahmed Al-HarrasiNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, PO Box 33, Nizwa, Oman. aharrasi@unizwa.edu.om.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sirtuin 3 (SIRT3) belongs to the Sirtuin protein family, which consists of NAD

Indexed as

Breast NeoplasmsMolecular Docking SimulationSirtuin 3Antineoplastic AgentsApoptosisCell Line, TumorCell ProliferationFemaleHumansMolecular Dynamics SimulationProtein BindingSmall Molecule LibrariesAntineoplastic AgentsSIRT3 protein, humanSirtuin 3Small Molecule LibrariesBreast cancerFlow cytometryInhibitorMolecular dockingMTT assaySIRT3

Identifiers

PMID38816444
PMCPMC11139978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.