ArticleEmerging infectious diseases2024
Newly Recognized Spotted Fever Group Rickettsia as Cause of Severe Rocky Mountain Spotted Fever-Like Illness, Northern California, USA.
Article in Emerging infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Improved Case Detection of Fleaborne Typhus by PCR Testing, Los Angeles County, California, USA, 2022-2024.Emerging infectious diseases · 2026Article
- Molecular Surveillance Reveals Diverse Tick-Borne Pathogens in Northern California.Pathogens (Basel, Switzerland) · 2026Article
- A real-time PCR assay for detection of Rickettsia rickettsii to aid in vivo infection monitoring.International journal of medical microbiology : IJMM · 2026Article
- Rickettsia lanei Rickettsiosis, Oregon, USA, 2025.Emerging infectious diseases · 2026Article
- Assessment of the Pathogenicity ofPathogens (Basel, Switzerland) · 2026Article
- Dermacentor occidentalis Ticks and Link to Rickettsia lanei Infections, California, USA.Emerging infectious diseases · 2026Article
- A rapid isothermal RPA-CRISPR/Cas12a assay for detection ofFrontiers in microbiology · 2026Article
- Isolation and Characterization of Rickettsia finnyi, Novel Pathogenic Spotted Fever Group Rickettsia in Dogs, United States.Emerging infectious diseases · 2025Article
- Rickettsial Pathogens in Dogs and Ticks During an Epidemic of Rocky Mountain Spotted Fever in Ensenada, Baja California, México.The American journal of tropical medicine and hygiene · 2025Article
- A new spotted fever group Rickettsia genotype in Haemaphysalis leporispalustris from Maine, USA.Ticks and tick-borne diseases · 2025Article
- Molecular Detection of SFGR in Ticks Collected from Yaks in Jiulong County of Sichuan Province, China.Animals : an open access journal from MDPI · 2025Article
- Severe and Fatal Rocky Mountain Spotted Fever After Exposure in Tecate, Mexico - California, July 2023-January 2024.MMWR. Morbidity and mortality weekly report · 2024Article
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Authors and funding
12 authors.
Funding
Abstract
The incidence of spotted fever group (SFG) rickettsioses in the United States has tripled since 2010. Rocky Mountain spotted fever, the most severe SFG rickettsiosis, is caused by Rickettsia rickettsii. The lack of species-specific confirmatory testing obfuscates the relative contribution of R. rickettsii and other SFG Rickettsia to this increase. We report a newly recognized rickettsial pathogen, Rickettsia sp. CA6269, as the cause of severe Rocky Mountain spotted fever-like illness in 2 case-patients residing in northern California. Multilocus sequence typing supported the recognition of this pathogen as a novel Rickettsia genotype most closely related to R. rickettsii. Cross-reactivity observed for an established molecular diagnostic test indicated that Rickettsia sp. CA6269 might be misidentified as R. rickettsii. We developed a Rickettsia sp. CA6269-specific real-time PCR to help resolve this diagnostic challenge and better characterize the spectrum of clinical disease and ecologic epidemiology of this pathogen.
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