Evidence map›Paper›PMID 38815228›Full record

ArticleBlood advances2024

Targeting CD38 with isatuximab and a novel CD38/CD3×CD28 trispecific T-cell engager in older patients with acute myeloid leukemia.

Esperanza Martín-Sánchez, Laura Blanco, Peter S Kim, Kamlesh Bisht, Hongfang Wang, Helgi Van de Velde, Tomas Jelinek, Catia Simoes, Felipe Prosper, Jesus F San Miguel and 8 more

Abstract read
In one paragraph

Article in Blood advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Esperanza Martín-SánchezCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0002-8155-9185
Laura BlancoCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0002-1859-0884
Peter S KimSanofi R&D, North America, Cambridge, MA.
Kamlesh BishtSanofi R&D, North America, Cambridge, MA.
Hongfang WangSanofi R&D, North America, Cambridge, MA.ORCID 0000-0002-1104-1540
Helgi Van de VeldeSanofi R&D, North America, Cambridge, MA.
Tomas JelinekCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.
Catia SimoesCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.
Felipe ProsperCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0001-6115-8790
Jesus F San MiguelCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0002-9183-4857
Ana AlfonsoCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0002-2478-5354
Juan BerguaHospital San Pedro de Alcántara, Cáceres, Spain.ORCID 0000-0001-8229-1208
Rebeca Rodríguez-VeigaHospital Universitario La Fe, Valencia, Spain.ORCID 0000-0003-2139-8540
Susana VivesInstitut Català d'Oncologia Badalona-Hospital Germans Trias I Pujol, Josep Carreras Research Institute, Badalona, Spain.
David Martínez-CuadrónHospital Universitario La Fe, Valencia, Spain.
Pau MontesinosHospital Universitario La Fe, Valencia, Spain.ORCID 0000-0002-3275-5593
Bruno PaivaCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0003-1977-3815
Aintzane ZabaletaCancer Center Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain.ORCID 0000-0003-3474-3040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADP-ribosyl Cyclase 1Antibodies, Monoclonal, HumanizedLeukemia, Myeloid, AcuteAgedAged, 80 and overAntibodies, BispecificCD28 AntigensCD3 ComplexFemaleHumansMaleMembrane GlycoproteinsT-LymphocytesADP-ribosyl Cyclase 1Antibodies, BispecificAntibodies, Monoclonal, HumanizedCD28 AntigensCD38 protein, humanCD3 ComplexisatuximabMembrane Glycoproteins

Identifiers

PMID38815228
PMCPMC11321322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.