Evidence map›Paper›PMID 38814918›Full record

ReviewJournal of experimental botany2025

Harnessing controlled-environment systems for enhanced production of medicinal plants.

Ajwal Dsouza, Mike Dixon, Mukund Shukla, Thomas Graham

Abstract readReview
In one paragraph

Review in Journal of experimental botany, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  15. Frontiers in pharmacology · 2025
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ajwal DsouzaControlled Environment Systems Research Facility, School of Environmental Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.ORCID 0000-0003-4415-2965
Mike DixonControlled Environment Systems Research Facility, School of Environmental Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.
Mukund ShuklaDepartment of Plant Agriculture, University of Guelph, Guelph, ON, N1G 2W1, Canada.ORCID 0000-0002-3580-3538
Thomas GrahamControlled Environment Systems Research Facility, School of Environmental Sciences, University of Guelph, Guelph, ON, N1G 2W1, Canada.ORCID 0000-0003-4576-5800

Funding

Natural Sciences and Engineering Research Council 577615-2022
6 · The paper itself

Abstract

Medicinal plants are valued for their contributions to human health. However, the growing demand for medicinal plants and the concerns regarding their quality and sustainability have prompted the reassessment of conventional production practices. Controlled-environment cropping systems, such as vertical farms, offer a transformative approach to production of medicinal plants. By enabling precise control over environmental factors, such as light, carbon dioxide, temperature, humidity, nutrients, and airflow, controlled environments can improve the consistency, concentration, and yield of bioactive phytochemicals in medicinal plants. This review explores the potential of controlled-environment systems for enhancing production of medicinal plants. First, we describe how controlled environments can overcome the limitations of conventional production in improving the quality of medicinal plants. Next, we propose strategies based on plant physiology to manipulate environmental conditions for enhancing the levels of bioactive compounds in plants. These strategies include improving photosynthetic carbon assimilation, light spectrum signalling, purposeful stress elicitation, and chronoculture. We describe the underlying mechanisms and practical applications of these strategies. Finally, we highlight the major knowledge gaps and challenges that limit the application of controlled environments, and discuss future research directions.

Indexed as

Environment, ControlledPlants, MedicinalCircadian clockcontrolled environmentfunctional genomicsLED lightmedicinal plantsphytopharmaceuticalsplant factoryplant stressspecialized metabolitesvertical farming

Identifiers

PMID38814918
PMCPMC11659182

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.