ArticleThe Journal of general virology2024
Decoding huge phage diversity: a taxonomic classification of Lak megaphages.
Article in The Journal of general virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Large-scale genomic analysis of jumbo phages: coevolution, genome architecture, and host interaction mechanisms.Animal microbiome · 2026Article
- Gut virome dynamics: from commensal to critical player in health and disease.Nature reviews. Gastroenterology & hepatology · 2026Review
- Bacteriophages in gut metagenomes: from analysis to application.Virology journal · 2026Review
- A novel lineage of large aquatic bacteriophages identified through metagenomics.Archives of virology · 2025Article
- Targeting multidrug-resistant Escherichia coli by two isolated bacteriophages from hospital wastewater.Folia microbiologica · 2025Article
- Unlocking the genomic repertoire of a cultivated megaphage.Npj viruses · 2025Article
- Summary of taxonomy changes ratified by the International Committee on Taxonomy of Viruses (ICTV) from the Bacterial Viruses Subcommittee, 2025.The Journal of general virology · 2025Article
- Towards a unifying phylogenomic framework for tailed phages.PLoS genetics · 2025Article
- Article
- Phage diversity in One Health.Essays in biochemistry · 2024Review
- A roadmap of isolating and investigating bacteriophage infecting human gut anaerobes.Essays in biochemistry · 2024Review
- Nanopore and Illumina sequencing reveal different viral populations from human gut samples.Microbial genomics · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-throughput sequencing for uncultivated viruses has accelerated the understanding of global viral diversity and uncovered viral genomes substantially larger than any that have so far been cultured. Notably, the Lak phages are an enigmatic group of viruses that present some of the largest known phage genomes identified in human and animal microbiomes, and are dissimilar to any cultivated viruses. Despite the wealth of viral diversity that exists within sequencing datasets, uncultivated viruses have rarely been used for taxonomic classification. We investigated the evolutionary relationships of 23 Lak phages and propose a taxonomy for their classification. Predicted protein analysis revealed the Lak phages formed a deeply branching monophyletic clade within the class
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.