Evidence map›Paper›PMID 38814471›Full record

ArticleActa neuropathologica2024

Alternatively spliced ELAVL3 cryptic exon 4a causes ELAVL3 downregulation in ALS TDP-43 proteinopathy.

Isabel Costantino, Alex Meng, John Ravits

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. TDP-43: [GU]-ardian of the transcriptome.Molecular neurodegeneration · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Isabel CostantinoDepartment of Neurosciences, ALS Translational Research, University of California San Diego, La Jolla, CA, USA.
Alex MengDepartment of Neurosciences, ALS Translational Research, University of California San Diego, La Jolla, CA, USA.
John RavitsDepartment of Neurosciences, ALS Translational Research, University of California San Diego, La Jolla, CA, USA. jravits@ucsd.edu.ORCID 0000-0001-6521-4649

Funding

U of Calif, San Diego Neuroscience Microscopy ImagingP30NS047101 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GLEESON, JOSEPH G, ZHENG, BINHAI · 2003 to 2022
$9.0M
Multidisciplinary training in basic and translational Alzheimer's disease researchT32AG066596 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BREWER, JAMES B · 2020 to 2024
$2.2M
ELAVL3 in ALS/FTDR21NS121805 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RAVITS, JOHN · 2021 to 2021
$417k
CSR NIH HHS P30 NS047101CSR NIH HHS R21 NS121805CSR NIH HHS T32 AG066596NIA NIH HHS T32 AG066596NINDS NIH HHS P30 NS047101NINDS NIH HHS R21 NS121805
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alternative SplicingAmyotrophic Lateral SclerosisDown-RegulationExonsDNA-Binding ProteinsFemaleHumansMaleMiddle AgedTDP-43 ProteinopathiesDNA-Binding ProteinsTARDBP protein, human

Identifiers

PMID38814471
PMCPMC11139733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.