Evidence map›Paper›PMID 38814458›Full record

ArticleJournal of natural products2024

Discovery of Biofilm Inhibitors from the Microbiota of Marine Egg Masses.

Lois Kyei, Karla Piedl, Carla Menegatti, Eleanor M Miller, Emily Mevers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lois KyeiDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID 0000-0002-8315-3488
Karla PiedlDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.
Carla MenegattiDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.
Eleanor M MillerDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.
Emily MeversDepartment of Chemistry, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID 0000-0001-7986-5610

Funding

Unlocking the biomedical potential of microbial symbionts from complex ecosystems; Admin Supplement for InstrumentationR35GM146740 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Emily Elizabeth Mevers · 2022 to 2026
$2.0M
NIGMS NIH HHS R35 GM146740
6 · The paper itself

Abstract

Biofilms commonly develop in immunocompromised patients, which leads to persistent infections that are difficult to treat. In the biofilm state, bacteria are protected against both antibiotics and the host's immune system; currently, there are no therapeutics that target biofilms. In this study, we screened a chemical fraction library representing the natural product capacity of the microbiota of marine egg masses, namely, the moon snail egg collars. This led to the identification of active fractions targeting both

Indexed as

Anti-Bacterial AgentsBiofilmsPseudomonas aeruginosaStaphylococcus aureusAnimalsBiological ProductsMarine BiologyMicrobial Sensitivity TestsMicrobiotaMolecular StructureSiderophoresSnailsAnti-Bacterial AgentsBiological ProductsSiderophores

Identifiers

PMID38814458
PMCPMC11217947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.