Evidence map›Paper›PMID 38814004›Full record

ArticleJournal of clinical laboratory analysis2024

Effects of Splenectomy on Natural Killer Cell Levels in β-Thalassemia Major Patients.

Ayşegül Uğur Kurtoğlu, Sevcan Uğur, Mesut Göçer, Erdal Kurtoğlu

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ayşegül Uğur KurtoğluDepartment of Biochemistry, Sağlık Bilimleri University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-6033-4139
Sevcan UğurDepartment of Rheumatology, Antalya City hospital, Antalya, Turkey.
Mesut GöçerDepartment of Hematology, Sağlık Bilimleri University, Istanbul, Turkey.ORCID https://orcid.org/0000-0002-0346-7154
Erdal KurtoğluDepartment of Hematology, Sağlık Bilimleri University, Istanbul, Turkey.

Funding

TÜBİTAK ULAKBİM Member Institutions for APC
6 · The paper itself

Abstract

aimIn this study, we investigated how splenectomy affects natural killer (NK) cell levels in patients with β-thalassemia major (β-TM). MATERIALS AND

methodsSeventy patients with β-TM (38 splenectomized and 32 nonsplenectomized) and 25 healthy controls were included in this study. The hemogram parameters, ferritin, T lymphocyte, T-helper cell, T-suppressor cell, and NK cell numbers, were measured.

resultsThe T lymphocyte (CD3

conclusionSplenectomy reduces NK cell levels in patients with β-TM. The negative relationship between ferritin levels and NK cells indicates that ferritin levels should be kept under control in patients with β-TM.

Indexed as

beta-ThalassemiaKiller Cells, NaturalSplenectomyAdolescentAdultCase-Control StudiesChildFemaleFerritinsHumansLymphocyte CountMaleYoung AdultFerritinsNK cellT‐helper cellT‐suppressor cellβ‐thalassemia major

Identifiers

PMID38814004
PMCPMC11137841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.