Evidence map›Paper›PMID 38813525›Full record

ArticleJournal of oral microbiology2024

Effects of efflux pumps on antifungal activity of chitosan against

Sureeporn Muangsawat, Patcharaporn Chaiyosang, Patrawee Sinkanarak, Juthamas Sukted, Panida Thanyasrisung, Oranart Matangkasombut

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sureeporn MuangsawatDepartment of Microbiology and Center of Excellence on Oral Microbiology and Immunology, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand.
Patcharaporn ChaiyosangDDS Program, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand.
Patrawee SinkanarakDDS Program, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand.
Juthamas SuktedGraduate Program in Applied Biological Sciences, Chulabhorn Graduate Institute, Bangkok, Thailand.
Panida ThanyasrisungDepartment of Microbiology and Center of Excellence on Oral Microbiology and Immunology, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-1378-695X
Oranart MatangkasombutDepartment of Microbiology and Center of Excellence on Oral Microbiology and Immunology, Faculty of Dentistry, Chulalongkorn University, Pathumwan, Bangkok, Thailand.ORCID https://orcid.org/0000-0003-4029-6830

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antifungal resistance is a major problem, commonly caused by drug-efflux pump overexpression. To evaluate if chitosan could be effective in drug-resistant Materials and Methods: The minimal fungicidal concentration (MFC) of oligomer (7-9 kD) and polymer (900-1,000 kD) chitosan against Results: While deleting any individual efflux pump genes had no effect on chitosan susceptibility, simultaneous deletion of multiple pumps (in Conclusion: Thus,

Indexed as

Antifungal agentCandida albicansChitosandrug resistanceefflux pumpSaccharomyces cerevisiae

Identifiers

PMID38813525
PMCPMC11133954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.