Evidence map›Paper›PMID 38813517›Full record

ArticleTurkish journal of medical sciences2023

Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris.

Ramadan Sayed Hussein, Salman Bin Dayel, Othman Abahussein

Abstract read
In one paragraph

Article in Turkish journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ramadan Sayed HusseinDepartment of Dermatology, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.ORCID https://orcid.org/0000-0003-3620-0648
Salman Bin DayelDepartment of Dermatology, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.ORCID https://orcid.org/0000-0001-9885-2372
Othman AbahusseinDepartment of Dermatology, College of Medicine, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.ORCID https://orcid.org/0009-0005-9920-7283

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Acne vulgaris (AV) is a common inflammatory skin condition associated with psychological and social distress. Its pathogenesis involves factors such as sebaceous hypersecretion and Materials and methods: One hundred patients with severe AV were enrolled, each receiving 0.75 mg/kg IOS treatment daily for 4 months. Serum 25 OH vitamin D levels were measured before, during, and after treatment. Results: This study found a significant increase in serum 25 OH vitamin D levels among patients with severe AV following IOS treatment (p < 0.001). Conclusion: This study suggests that AV may negatively impact vitamin D synthesis, but IOS treatment appears to raise vitamin D serum levels in individuals with severe AV. Further research is needed to confirm the potential relationship between AV and vitamin D levels.

Indexed as

Acne VulgarisDermatologic AgentsIsotretinoinVitamin DAdolescentAdultFemaleHumansMaleProspective StudiesYoung Adult25-hydroxyvitamin DDermatologic AgentsIsotretinoinVitamin DAcne vulgarisisotretinoinvitamin D

Identifiers

PMID38813517
PMCPMC10760531

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.