Evidence map›Paper›PMID 38813482›Full record

ArticleTurkish journal of medical sciences2023

Is electrophysiological study a novel predictor for permanent pacemaker implantation after transcatheter aortic valve implantation?

Zeki Çetinkaya, Deniz Elçik, Şaban Keleşoğlu, Burak Cesur, Mustafa Yaşan, Uğur Karabiyik, Bilge Bingöl, Nihat Kalay, Ramazan Topsakal, Aydın Tunçay and 2 more

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Article in Turkish journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

12 authors.

Zeki ÇetinkayaDepartment of Cardiology, Elazığ Fethi Sekin City Hospital, Elazığ, Turkiye.ORCID https://orcid.org/0000-0003-0434-3433
Deniz ElçikDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0003-0992-1415
Şaban KeleşoğluDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0001-6249-9220
Burak CesurDepartment of Cardiology, Kayseri State Hospital, Kayseri, Turkiye.ORCID https://orcid.org/0000-0002-3943-1006
Mustafa YaşanDepartment of Cardiology, Kastamonu Training and Research Hospital, Kastamonu, Turkiye.ORCID https://orcid.org/0000-0003-0741-9720
Uğur KarabiyikDepartment of Cardiology, Niğde Training and Research Hospital, Niğde, Turkiye.ORCID https://orcid.org/0000-0002-5644-751X
Bilge BingölDepartment of Cardiology, Kırşehir Training and Research Hospital, Kırşehir, Turkiye.ORCID https://orcid.org/0000-0001-5110-385X
Nihat KalayDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0001-5800-7094
Ramazan TopsakalDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0003-4155-8206
Aydın TunçayDepartment of Cardio Vascular Surgery Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0001-8877-2547
Ali DoğanDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0002-7756-0626
Mehmet Tuğrul InançDepartment of Cardiology, Faculty of Medicine, Erciyes University, Kayseri, Turkiye.ORCID https://orcid.org/0000-0002-3253-4889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: Despite advancements in valve technology and increased clinical experience, complications related to conduction defects after transcatheter aortic valve implantation (TAVR) have not improved as rapidly as expected. In this study, we aimed to predict the development of complete atrioventricular (AV) block and bundle branch block during and after the TAVR procedure and to investigate any changes in the cardiac conduction system before and after the procedure using electrophysiological study. Materials and methods: A total of 30 patients who were scheduled for TAVR at our cardiovascular council were planned to be included in the study. TAVR was performed on patients at Erciyes University Medical Faculty Hospital as a single center between May 2019 and August 2020 Diagnostic electrophysiological study was performed before the TAVR procedure and after its completion. Changes in the cardiac conduction system during the preprocedure, intra-procedure, and postprocedure periods were recorded. Results: Significant increases in baseline cycle length, atrial-His (AH) interval, his-ventricular (HV) interval and atrioventricular (AV) distance were observed before and after the TAVR procedure (p = 0.039, p < 0.001, p = 0.018, p < 0.001, respectively). During the TAVR procedure, the preprocedural HV interval was longer in patients who developed AV block and bundle branch block compared to those who did not and this difference was statistically significant (p = 0.024). ROC curve analysis revealed that a TAVR preprocedure HV value >59.5 ms had 86% specificity and 75% sensitivity in detecting AV block and bundle branch block (AUC = 0.83, 95% CI: 0.664-0.996, p = 0.013). The preprocedure HV distance was 98 ± 10.55ms in the group with permanent pacemaker implantation and the mean value in the group without permanent pacemaker implantation was 66.27 ± 15.55 ms, showing a borderline significant difference (p = 0.049). Conclusion: The prolongation of HV interval in patients with AV block and bundle branch block suggests that the block predominantly occurs at the infra-hisian level. Patients with longer preprocedural HV intervals should be closely monitored for the need for permanent pacemaker implantation after the TAVR procedure.

Indexed as

Atrioventricular BlockPacemaker, ArtificialTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisBundle-Branch BlockElectrocardiographyFemaleHeart Conduction SystemHumansMalePostoperative Complicationsatrial-his intervalAV blockbundle branch blockTranscatheter aortic valve implantation

Identifiers

PMID38813482
PMCPMC10760562

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.