Evidence map›Paper›PMID 38813393›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2024

Machine Perfusion Enables 24-h Preservation of Vascularized Composite Allografts in a Swine Model of Allotransplantation.

Marion Goutard, Pierre Tawa, Yanis Berkane, Alec R Andrews, Casie A Pendexter, Reinier J de Vries, Victor Pozzo, Golda Romano, Hyshem H Lancia, Irina Filz von Reiterdank and 7 more

Abstract read
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. 24-hourFrontiers in transplantation · 2026
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Marion Goutard *Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Pierre Tawa *Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Yanis BerkaneDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Alec R AndrewsDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Casie A PendexterHarvard Medical School, Boston, MA, United States.
Reinier J de VriesHarvard Medical School, Boston, MA, United States.
Victor PozzoDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Golda RomanoDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Hyshem H LanciaDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Irina Filz von ReiterdankDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Nicolas BertheuilSuivi Immunologique des Thérapeutiques Innovantes Laboratory, INSERM U1236, University of Rennes 1, Rennes, France.
Ivy A RosalesImmunopathology Research Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, United States.
Ira Doressa Anne L HowImmunopathology Research Laboratory, Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, United States.
Mark A RandolphDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Alexandre G LellouchDivision of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Curtis L Cetrulo *Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston, MA, United States.
Korkut Uygun *Harvard Medical School, Boston, MA, United States.

Funding

Genetic-engineered control of the immunogeneic state of vascular composite allografts during preservationR01EB028782 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Biju Parekkadan, Korkut Uygun · 2021 to 2026
$3.1M
NIBIB NIH HHS R01 EB028782
6 · The paper itself

Abstract

The current gold standard for preserving vascularized composite allografts (VCA) is 4°C static cold storage (SCS), albeit muscle vulnerability to ischemia can be described as early as after 2 h of SCS. Alternatively, machine perfusion (MP) is growing in the world of organ preservation. Herein, we investigated the outcomes of oxygenated acellular subnormothermic machine perfusion (SNMP) for 24-h VCA preservation before allotransplantation in a swine model. Six partial hindlimbs were procured on adult pigs and preserved

Indexed as

Graft SurvivalOrgan PreservationPerfusionVascularized Composite AllotransplantationAllograftsAnimalsComposite Tissue AllograftsHindlimbModels, AnimalSwineTransplantation, Homologousischemia-reperfusion injuriesmachine perfusionorgan preservationvascularized composite allotransplantationVCA

Identifiers

PMID38813393
PMCPMC11133529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.