Evidence map›Paper›PMID 38813361›Full record

ReviewJournal of medicine and life2024

SLE and multiple myeloma: an underlooked link? A review of case reports from the last decade.

Rupak Desai, Sanjana Devaragudi, Loveneet Kaur, Kulwinder Singh, Jerrin Bawa, Nyein Wint Yee Theik, Spandana Palisetti, Akhil Jain

Abstract readReview
In one paragraph

Review in Journal of medicine and life, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rupak DesaiIndependent Researcher, Atlanta, GA, USA.
Sanjana DevaragudiDepartment of Medicine, Apollo Institute of Medical Sciences and Research, Hyderabad, India.
Loveneet KaurDepartment of Medicine, Government Medical College, Patiala, India.
Kulwinder SinghDepartment of Medicine, Government Medical College, Patiala, India.
Jerrin BawaDepartment of Internal Medicine, Flushing Hospital Medical Center, NY, USA.
Nyein Wint Yee TheikDepartment of Internal Medicine, Memorial Healthcare System, Hollywood, FL, USA.
Spandana PalisettiDepartment of Medicine, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India.
Akhil JainDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) affects multiple organ systems, and there has recently been increasing evidence that suggests a considerable rise in cancer risk. Despite growing evidence, the relationship between SLE and multiple myeloma (MM) remains underlooked. This review synthesizes findings from case reports published between 2012 and 2023 to explore this relationship. We conducted a comprehensive search using PubMed, Embase, and Google Scholar with the keywords 'SLE' and 'multiple myeloma' and described the clinical profile of MM in patients with SLE. Seven case reports were reviewed. Five case reports included female participants, two had a simultaneous diagnosis of SLE and MM, and in others, MM followed SLE varying from 7 months to 30 years. Two cases reported an improvement in MM. Four cases reported death due to complications, which included shock, myocardial infarction, and pneumonia. Lupus nephritis was seen to complicate MM and SLE complex in 2 cases. Larger, well-developed studies focusing on clinical presentation, diagnostic strategy, treatment, and outcomes are needed to better understand the association between SLE and MM. Healthcare workers should be aware of the increased risk of malignancy in SLE and customize screening accordingly.

Indexed as

Lupus Erythematosus, SystemicMultiple MyelomaAdultAgedCase Reports as TopicFemaleHumansMaleMiddle Agedlupusmultiple myelomamyelomaSLE

Identifiers

PMID38813361
PMCPMC11131644

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.