Evidence map›Paper›PMID 38813360›Full record

ArticleJournal of medicine and life2024

Salivary levels of azurocidin and soluble azurophilic granules in periodontal disease.

Fatima Sabah Jasim, Batool Hassan Al-Ghurabi, Lubaba Abdulsamad Abdulameer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicine and life, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatima Sabah JasimDepartment of Basic Science of Oral Microbiology, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Batool Hassan Al-GhurabiDepartment of Basic Science, College of Dentistry, University of Baghdad, Baghdad, Iraq.
Lubaba Abdulsamad AbdulameerDepartment of Periodontics, College of Dentistry, University of Baghdad, Baghdad, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontitis is an infection-driven inflammatory condition of the periodontium. Neutrophils are one of the most important first-line immune cells that protect against pathogen microorganisms in the saliva, but they may also mediate tissue death in inflammatory disorders. The aim of our study was to estimate salivary levels of azurocidin and extracellular azurophilic granules cluster of differentiation (CD63) as biomarkers of neutrophil activation in patients with periodontal diseases and to study the correlation between the levels of these two biomarkers and clinical periodontal parameters. The study included 60 patients with periodontal disease (30 patients with periodontitis and 30 with gingivitis) and 25 healthy controls. The assessed parameters were bleeding on probing, the plaque index, clinical attachment loss, and probing pocket depth. Saliva samples were taken from each study participant, and azurocidin and CD63 levels were measured using ELISA. Azurocidin and CD63 levels were significantly higher in patients with periodontitis and patients with gingivitis than in controls (

Indexed as

BiomarkersPeriodontal DiseasesSalivaAdultAntimicrobial Cationic PeptidesBlood ProteinsCase-Control StudiesFemaleGingivitisHumansMaleMiddle AgedNeutrophilsPeriodontitisSalivary Proteins and PeptidesAntimicrobial Cationic PeptidesAZU1 protein, humanBiomarkersBlood ProteinsSalivary Proteins and Peptidesazurocidinazurophilic granuleCD63neutrophilsperiodontal disease

Identifiers

PMID38813360
PMCPMC11131640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.