Evidence map›Paper›PMID 38813053›Full record

ArticleWorld journal of gastroenterology2024

Expanding indications for chronic hepatitis B treatment: Is it really desirable to treat everyone?

Fabiola Di Dato, Raffaele Iorio

Abstract readEditorial
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fabiola Di DatoDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples 80131, Italy.
Raffaele IorioDepartment of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples 80131, Italy. riorio@unina.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic viral hepatitis causes an increased risk of progressive liver disease and hepatocellular carcinoma. On the wave of the World Health Organization's goal to reduce new cases and deaths from hepatitis B and C by 2030, there is an increasing call to expand the indications for treatment of chronic hepatitis B. Currently, the main goal of treatment is to achieve a functional cure due to the inability of current drugs to completely eradicate the virus. There are still many discrepancies between available guidelines in terms of eligibility for treatment as well as an uncertainty about the appropriate treatment duration. This editorial addresses key questions about the topic and whether indications for treatment should be expanded.

Indexed as

Antiviral AgentsHepatitis B, ChronicHepatitis B virusLiver NeoplasmsPractice Guidelines as TopicCarcinoma, HepatocellularHumansPatient SelectionTreatment OutcomeAntiviral AgentsChildrenFunctional cureHepatitis B virusInterferonNucleos(t)ide analogues

Identifiers

PMID38813053
PMCPMC11130575

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.