Evidence map›Paper›PMID 38813035›Full record

ArticleTurkish journal of medical sciences2023

Clinical and laboratory features in health care volunteers with inactivated SARS-CoV-2 vaccination.

Zhijie Li, Yafang Wan, Lanlan Xu, Wenjia Zhang, Yu Zhang, Pu Liao

Abstract read
In one paragraph

Article in Turkish journal of medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhijie Li *Chongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-0662-6800
Yafang Wan *Department of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.ORCID https://orcid.org/0000-0001-7786-1341
Lanlan XuDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.ORCID https://orcid.org/0000-0003-2344-0183
Wenjia ZhangDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.ORCID https://orcid.org/0000-0002-6581-2443
Yu ZhangDepartment of Clinical Laboratory, Chongqing General Hospital, Chongqing, China.ORCID https://orcid.org/0000-0003-2683-5164
Pu LiaoChongqing Medical University, Chongqing, China.ORCID https://orcid.org/0000-0002-9091-0758

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: To better optimize the inactivated vaccine-induced immune response and improve vaccine protection efficiency, a preliminary study was conducted on the influencing factors of producing neutralizing antibody (NAb) titers against the inactivated coronavirus disease 2019 (COVID-19) vaccine. Materials and methods: A total of 91 health care volunteers were enrolled from the Immunology Division of the Laboratory Department of Chongqing General Hospital from February to March 2021. The study had a cross-sectional design. All of the volunteers were scheduled to receive a complete dose regimen of the inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine and the vaccination interval between 2 doses was 14 days. Clinical and laboratory features were collected for further analysis. Results: The NAb titers gradually increased after COVID-19 vaccination, and 72.53% (n = 66) of the volunteers had NAbs after the second dose. Eight variables, including CD16 Conclusion: The NAbs titers of the inactivated vaccines were positively correlated with the ratio of CD19

Indexed as

COVID-19COVID-19 VaccinesSARS-CoV-2Vaccines, InactivatedAdultAntibodies, NeutralizingAntibodies, ViralCross-Sectional StudiesFemaleHumansKiller Cells, NaturalMaleMiddle AgedVaccinationAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesSARS-CoV-2 inactivated vaccinesVaccines, InactivatedCD19COVID-19healthcareIL-2IL-6vaccination

Identifiers

PMID38813035
PMCPMC10763784

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.