Evidence map›Paper›PMID 38812836›Full record

ArticleSAGE open medical case reports2024

Reversible posterior leukoencephalopathy syndrome following carboplatin and paclitaxel in cervical cancer: Case report.

Karima Ouchane, Fatima Zahra Bellefkih, Nadia Benchakroun, Mouna Bourhafour, Tarik Chekrine, Zineb Bouchbika, Hassan Jouhadi, Nezha Tawfiq, Souha Sahraoui

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karima OuchaneOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.ORCID https://orcid.org/0009-0008-7165-557X
Fatima Zahra BellefkihRadiation Oncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Nadia BenchakrounOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Mouna BourhafourOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Tarik ChekrineOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Zineb BouchbikaOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Hassan JouhadiOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Nezha TawfiqOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.
Souha SahraouiOncology Department, Mohammed IV Cancer Treatment Center, Ibn Rochd Hospital University, Hassan II University, Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Posterior reversible leukoencephalopathy is a rare radio-clinical entity that has gained increasing recognition over the last two decades. It is associated with various etiologies: arterial hypertension, autoimmune diseases, chemotherapy, and immunosuppressive drugs. Several cases have already been reported following cancer therapy. Posterior reversible leukoencephalopathy is characterized by capital clinical signs (headache, seizures, confusional syndrome, and visual disorders) and radiological abnormalities (cerebral edema predominantly in the posterior regions). We report the case of a 38-year-old female patient diagnosed with posterior reversible leukoencephalopathy after receiving Carboplatin and Paclitaxel chemotherapy for recurrent cervical cancer, which was revealed by a generalized seizure. Brain magnetic resonance imaging showed T2 Flair hyper signals in the parieto-occipital regions. This complication is rare but is probably underdiagnosed due to a lack of awareness and limited hindsight. Rapid diagnosis is essential to prevent acute neurological complications, which can be life-threatening or functionally crippling regardless of neoplasia.

Indexed as

cervical cancerconvulsionmagnetic resonance imagingpaclitaxel and carboplatinReversible posterior leukoencephalopathy syndrome

Identifiers

PMID38812836
PMCPMC11135113

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.