Evidence map›Paper›PMID 38812719›Full record

ReviewFrontiers in allergy2024

Pre-asthma: a useful concept? A EUFOREA paper. Part 2-late onset eosinophilic asthma.

G K Scadding, C Gray, D M Conti, M McDonald, V Backer, G Scadding, M Bernal-Sprekelsen, E De Corso, Z Diamant, C Hopkins and 12 more

Abstract readReview
In one paragraph

Review in Frontiers in allergy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

G K ScaddingDepartment of Allergy & Rhinology, Royal National ENT Hospital, London, United Kingdom.
C GrayPaediatric Allergist, Red Cross Children's Hospital and University of Cape Town, Cape Town, South Africa.
D M ContiThe European Forum for Research and Education in Allergy and Airway Diseases Scientific Expert Team Members, Brussels, Belgium.
M McDonaldThe Allergy Clinic, Blairgowrie, Randburg, South Africa.
V BackerDepartment of Otorhinolaryngology, Head & Neck Surgery, and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
G ScaddingAllergy, Royal Brompton Hospital, London, United Kingdom.
M Bernal-SprekelsenOtolaryngology-Department, Clinic Barcelona, Barcelona, Spain.
E De CorsoOtolaryngology Head and Neck Surgery, A. Gemelli University Hospital Foundation IRCCS, Rome, Italy.
Z DiamantDepartment of Respiratory Medicine & Allergology, Institute for Clinical Science, Skane University Hospital, Lund University, Lund, Sweden.
C HopkinsDepartment of Rhinology and Skull Base Surgery, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom.
M JesenakDepartment of Clinical Immunology and Allergology, University Teaching Hospital in Martin, Martin, Slovak Republic.
P JohansenDepartment of Dermatology, University of Zurich, Zurich, Switzerland.
J KappenDepartment of Pulmonology, STZ Centre of Excellence for Asthma, COPD and Respiratory Allergy, Franciscus Gasthuis & Vlietland, Rotterdam, Netherlands.
J MullolRhinology Unit and Smell Clinic, ENT Department, Hospital Clínic, FRCB-IDIBAPS, Universitat de Barcelona, CIBERES, Barcelona, Spain.
D PriceObservational and Pragmatic Research Institute, Singapore, Singapore.
S QuirceDepartment of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain.
S ReitsmaDepartment of Otorhinolarynogology and Head/Neck Surgery, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, Netherlands.
S Toppila-SalmiDepartment of Otorhinolaryngology, Kuopio University Hospital and University of Eastern Finland, Kuopio, Finland.
B SeniorDepartment of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
J P ThyssenDepartment of Dermatology, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark.
U WahnDepartment for Pediatric Pneumology and Immunology, Charite University Medicine, Berlin, Germany.
P W HellingsDepartment of Otorhinolaryngology-Head and Neck Surgery, University Hospitals, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The concept of pre-diabetes has led to provision of measures to reduce disease progression through identification of subjects at risk of diabetes. We previously considered the idea of pre-asthma in relation to allergic asthma and considered that, in addition to the need to improve population health via multiple measures, including reduction of exposure to allergens and pollutants and avoidance of obesity, there are several possible specific means to reduce asthma development in those most at risk (pre- asthma). The most obvious is allergen immunotherapy (AIT), which when given for allergic rhinitis (AR) has reasonable evidence to support asthma prevention in children (2) but also needs further study as primary prevention. In this second paper we explore the possibilities for similar actions in late onset eosinophilic asthma.

Indexed as

chronic rhinosinusitis with nasal polypseosinophilslate onset asthmamast cellsnon-allergic rhinitisS. aureus biofilmvirulence genes

Identifiers

PMID38812719
PMCPMC11133565

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.