ArticleFrontiers in microbiology2024
Genetic and virulence characteristics of hybrid Shiga toxin-producing and atypical enteropathogenic
Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Comparison of hybrid-and mono-pathotype Escherichia coli isolates from South Korea based on whole genome analysis and cytotoxicity assay.Journal of biomedical science · 2026Article
- Genomic Insights into Ciprofloxacin-Resistant EnteropathogenicAntibiotics (Basel, Switzerland) · 2026Article
- Complete genomes of hybridMicrobiology resource announcements · 2025Article
- Article
- The Global Prevalence of Antibiotic Resistance and Shiga Toxin-ProducingAntibiotics (Basel, Switzerland) · 2025Review
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Authors and funding
11 authors.
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Abstract
Introduction: The predominant hybrid pathogenic Aim: In this work, genome-based characteristic analysis and cell-based assay of hybrid STEC/aEPEC strains isolated from livestock feces, animal source foods, and water in South Korea was performed. Methods: To identify the virulence and antimicrobial resistance genes, determining the phylogenetic position of hybrid STEC/aEPEC strains isolated in South Korea, a combination of real-time PCR and whole-genome sequencing (WGS) was used. Additionally, to assess the virulence of the hybrid strains and compare them with genomic characterization, we performed a cell cytotoxicity and invasion assays. Results: The hybrid STEC/aEPEC strains harbored Conclusion: Through genome-based characterization, we confirmed that the hybrid STEC/aEPEC strains are likely EPEC strains that have acquired STEC virulence genes via phage. Furthermore, our results emphasize the potential increased danger to humans posed by hybrid STEC/aEPEC strains isolated in South Korea, containing both
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