ReviewTouchREVIEWS in endocrinology2024
Obesity and Oral Health: The Link Between Adipokines and Periodontitis.
Review in TouchREVIEWS in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Biomarkers for differentiating diabetic periodontitis from chronic periodontitis: a systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- Inflammatory Association between Periodontal Disease and Systemic Health.Inflammation · 2025Pooled it
- Salivary asprosin, IL-39, IL-40, and IL-1β levels in diabetic patients with periodontitis: A cross-sectional analysis.Clinical oral investigations · 2026Trial
- Review
- Serum and gingival crevicular fluid asprosin levels in obese and normal-weight individuals with and without periodontitis: a cross-sectional study.BMC oral health · 2026Article
- Association between childhood obesity, salivary adiponectin, and total dental caries experience (dmft + DMFT) in children: a cross-sectional study.Scientific reports · 2026Article
- Periodontal disease and endocrine imbalance: a molecular pathways perspective.Frontiers in dental medicine · 2026Review
- The Oral Microbiome, Oral Hyperpermeability, and Periodontitis in Metabolic Syndrome.Advances in experimental medicine and biology · 2026Review
- Oral and cardiometabolic health through the lens of biobanks and large-scale epidemiologic research.Frontiers in oral health · 2026Review
- Proactive Strategies to Prevent Biofilm-Associated Infections: From Mechanistic Insights to Clinical Translation.Microorganisms · 2025Review
- Salivary Biomarker Profile in Periodontal Diseases: A Cross-Sectional Study on Leptin, Adiponectin, and Calprotectin.Diagnostics (Basel, Switzerland) · 2025Article
- Analysis of subgingival microbial community structure in MAFLD patients with periodontitis.Clinical oral investigations · 2025Article
- Is there a relationship between periodontal conditions and asprosin levels in gingival crevicular fluid, saliva and serum?BMC oral health · 2025Observational
- Association of oral health status with overweight and obesity in older adults aged ≥ 65 years- evidence from Chinese communities.BMC public health · 2025Article
- Prevalence of Oral Diseases and the Influence of the Presence of Overweight/Obesity in Schoolchildren Population in Mallorca.Journal of clinical medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a chronic inflammatory disease of the periodontium, or the supportive tissues around the tooth. This disease has been related to different risk factors, such as the presence of plaque and calculus, tobacco smoking, low socioeconomic status, and the immune state of the host. Importantly, the chronic inflammatory environment generated by periodontitis may lead to tooth loss and diverse systemic complications, such as cardiovascular disease, osteoarthritis and metabolic disease. Recent investigations have supported the role of obesity as a risk factor for periodontitis. Furthermore, studies have found obesity to compromise healing after periodontal therapy; however, the mechanisms underlying this association are not well understood. Proteins called 'adipokines' could be the factor linking obesity to periodontitis. Adipokines are bioactive molecules with hormonal properties and a structure similar to cytokines produced by the adipose tissue. Although adipokines have both pro-and anti-inflammatory effects, the shift towards pro-inflammatory actions occurs when the adipose tissue becomes pathological, as observe in the progression of conditions such as obesity or adiposopathy. This article reviews the role of adipokines in the pathophysiology and progression of periodontitis by focusing on their impact on inflammation and the molecular mechanisms through which adipokines contribute to the onset and development of periodontitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.