Evidence map›Paper›PMID 38812544›Full record

ArticleiScience2024

IGF2BP2-Shox2 axis regulates hippocampal-neuronal senescence to alleviate microgravity-induced recognition disturbance.

Yujie Zhao, Guohua Ji, Sihai Zhou, Shiou Cai, Kai Li, Wanyu Zhang, Chuanjie Zhang, Na Yan, Shuhui Zhang, Xiaopeng Li and 2 more

Abstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Gut microbes · 2026
    Article
  2. Deficiency of the mCellular and molecular life sciences : CMLS · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Histone Lactylation Contributes to Neuropathic Pain by Facilitating mThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yujie ZhaoState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Guohua JiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Sihai ZhouState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Shiou CaiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Kai LiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Wanyu ZhangBasic Medical Sciences, Capital Medical University School, Beijing, China.
Chuanjie ZhangState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Na YanState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Shuhui ZhangState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Xiaopeng LiState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.
Bo SongDepartment of Pathology and Forensics, Dalian Medical University, Dalian, China.
Lina QuState Key Laboratory of Space Medicine, China Astronaut Research and Training Center, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During space travel, microgravity leads to disturbances in cognitive function, while the underlying mechanism is still unclear. Simulated microgravity mice showed neuronal age-like changes in the hippocampus of our study. In the context of microgravity, we discovered m6A modification reshapes in the hippocampal region. When paired with RNA-seq and MeRIP-seq,

Indexed as

Behavioral neuroscienceCell biologyMolecular biologyNeuroscienceSpace sciences

Identifiers

PMID38812544
PMCPMC11134919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.