Evidence map›Paper›PMID 38811888›Full record

Trial reportBMC nephrology2024

Effects of different inspiratory muscle training protocols on functional exercise capacity and respiratory and peripheral muscle strength in patients with chronic kidney disease: a randomized study.

Nihan Katayıfçı, İrem Hüzmeli, Döndü İri Ş, Faruk Hilmi Turgut

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06401135 nacompletednot on this map

Effects of Different Inspiratory Muscle Training Protocols on Functional Exercise Capacity and Respiratory and Peripheral Muscle Strength in Patients With Chronic Kidney Disease: A Randomized Study

TypeinterventionalSponsorMustafa Kemal UniversityRan2021 to 2022Enrolled47ConditionsChronic Kidney Diseases, Inspiratory Muscle Training, Exercise CapacityArmsInspiratory muscle training
NCT07094347 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Intradialytic Inspiratory Muscle Training on Functional Capacity in Hemodialysis Patients

TypeinterventionalSponsorBaskent UniversityRan2025 to 2026Enrolled34ConditionsHemodialysisArmsinspiratory muscle training
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Effects of Progressive Inspiratory Muscle Training on Lung Volume and Respiratory Strength in Patients With Pre-Dialysis Chronic Kidney Disease.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Trial
  2. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nihan KatayıfçıDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Hatay Mustafa Kemal University, Hatay, Turkey. nkatayifci@mku.edu.tr.
İrem HüzmeliDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Hatay Mustafa Kemal University, Hatay, Turkey.
Döndü İri ŞDepartment of Physiotherapy and Rehabilitation, Institute of Health Sciences,, Hatay Mustafa Kemal University, Hatay, Turkey.
Faruk Hilmi TurgutDepartment of Nephrology, Tayfur Ata Sokmen Faculty of Medicine, Hatay Mustafa Kemal University, Hatay, Turkey.

Funding

Hatay Mustafa Kemal University Coordination Office of Scientific Research Projects 21.GAP.033
6 · The paper itself

Abstract

backgroundPathological changes were observed in the diaphragm due to abnormal renal function in chronic kidney disease (CKD). Inspiratory muscle training (IMT) has been suggested for patients with CKD; however, the most appropriate intensity for IMT has not been determined. Therefore, this study aimed to investigate the effects of different IMT protocols on respiratory muscle strength, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), functional exercise capacity, quality of life (QoL), pulmonary function, dyspnoea, fatigue, balance, and physical activity (PA) levels in patients with CKD.

methodsThis randomized, controlled, single-blind study included 47 patients and they were divided into three groups: Group 1 (n = 15, IMT with 10% maximal inspiratory pressure (MIP)), Group 2 (n = 16, IMT with 30% MIP), and Group 3(n = 16; IMT with 60% MIP). MIP, maximal expiratory pressure (MEP), 6-min walking test (6-MWT), QMS, HGS, QoL, pulmonary function, dyspnoea, fatigue, balance, and PA levels were assessed before and after eight weeks of IMT.

resultsIncreases in MIP, %MIP, 6-MWT distance, and %6-MWT were significantly higher in Groups 2 and 3 than in Group 1 after IMT (p < 0.05). MEP, %MEP, FEF

conclusionsIMT with 30% and 60% MIP similarly improves inspiratory muscle strength and functional exercise capacity. IMT with 30% is more effective in increasing PA. IMT is a beneficial method to enhance peripheral and expiratory muscle strength, respiratory function, QoL and balance, and reduce dyspnoea and fatigue. IMT with %30 could be an option for patients with CKD who do not tolerate higher intensities.

trial registrationThis study was retrospectively registered (NCT06401135, 06/05/2024).

Indexed as

Breathing ExercisesExercise ToleranceMuscle StrengthQuality of LifeRenal Insufficiency, ChronicRespiratory MusclesAdultAgedDyspneaFemaleHand StrengthHumansMaleMiddle AgedSingle-Blind MethodChronic kidney diseaseDyspnoeaExercise testMuscle strengthRespiratory muscle training

Identifiers

PMID38811888
PMCPMC11137907

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.