ArticleNature genetics2024
Cross-ancestry genome-wide association studies of brain imaging phenotypes.
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Article in Nature genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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20citing papers in PubMed, 2 pooled it
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The genetic architecture of brainstem structures.Nature communications · 2025Pooled it
- Cross-ancestry genome-wide association study identifies new susceptibility genes for preeclampsia.BMC pregnancy and childbirth · 2025Pooled it
- Brain imaging-wide exploration of site-specific pain: genetic correlation and Mendelian randomization study.Psychological medicine · 2026Article
- Cross-ancestry pleiotropic analysis of imaging-derived phenotypes enhances risk stratification of depression.Molecular psychiatry · 2026Article
- Cross-ancestry genetic architecture reveals shared biological pathways of major psychiatric disorders.Molecular psychiatry · 2026Article
- The genetic architecture of cortical similarity networks.Nature communications · 2026Article
- Trans-ethnic estimation and implications of genetic impact on continuous glycemic profiles.Cell discovery · 2026Article
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- Learning dynamics of unsupervised deep learning reveal epoch-specific genetic architectures of brain morphology.bioRxiv : the preprint server for biology · 2026Article
- Genome-Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Interpretable multimodal learning for integrating neuroimaging and genetic data in Alzheimer's disease.Frontiers in radiology · 2026Article
- Genetic underpinnings and causal effects of brain structure and function on chronic pain intensity.Nature communications · 2025Article
- Genetic and neural mechanisms shared by schizophrenia and depression.Molecular psychiatry · 2025Article
- Population-specific brain charts reveal Chinese-Western differences in neurodevelopmental trajectories.bioRxiv : the preprint server for biology · 2025Article
- Distinct effects of early-stage and late-stage socioeconomic factors on brain and behavioral traits.Nature neuroscience · 2025Article
- PennPRS: a centralized cloud computing platform for efficient polygenic risk score training in precision medicine.medRxiv : the preprint server for health sciences · 2025Article
- Reduced Cortical Surface Area in the Frontal Operculum as a Causal Risk Predictor for Chronic Pain.Pain research & management · 2025Article
- Genome-wide Pleiotropy Analysis Reveals Shared Genetic Associations between Type 2 Diabetes Mellitus and Subcortical Brain Volumes.Research (Washington, D.C.) · 2025Article
- Structural MRI of brain similarity networks.Nature reviews. Neuroscience · 2025Review
- Multi-Omics Integration Analysis Pinpoint Proteins Influencing Brain Structure and Function: Toward Drug Targets and Neuroimaging Biomarkers for Neuropsychiatric Disorders.International journal of molecular sciences · 2024Article
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Authors and funding
45 authors.
Jilian Fu *Department of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Quan Zhang *Department of Radiology, Characteristic Medical Center of Chinese People's Armed Police Force, Tianjin, China.
Jianhua Wang *Department of Bioinformatics, the Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.
Meiyun WangDepartment of Radiology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou, China.ORCID http://orcid.org/0000-0003-4454-5005
Bing ZhangDepartment of Radiology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, China.
Wenzhen ZhuDepartment of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0001-6252-9450
Shijun QiuDepartment of Medical Imaging, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Zuojun GengDepartment of Medical Imaging, the Second Hospital of Hebei Medical University, Shijiazhuang, China.
Guangbin CuiFunctional and Molecular Imaging Key Lab of Shaanxi Province and Department of Radiology, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yongqiang YuDepartment of Radiology, the First Affiliated Hospital of Anhui Medical University, Hefei, China.
Weihua LiaoDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Hui ZhangDepartment of Radiology, the First Hospital of Shanxi Medical University, Taiyuan, China.
Bo GaoDepartment of Radiology, the Affiliated Hospital of Guizhou Medical University, Guiyang, China.
Xiaojun XuDepartment of Radiology, the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, China.ORCID http://orcid.org/0000-0002-0127-2812
Tong HanDepartment of Radiology, Tianjin Huanhu Hospital, Tianjin, China.
Zhenwei YaoDepartment of Radiology, Huashan Hospital, Fudan University, Shanghai, China.
Wen QinDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.ORCID http://orcid.org/0000-0002-9121-8296
Feng LiuDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.ORCID http://orcid.org/0000-0002-3570-4222
Meng LiangSchool of Medical Imaging and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University, Tianjin, China.
Sijia WangSchool of Medical Imaging and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University, Tianjin, China.ORCID http://orcid.org/0000-0001-8949-303X
Qiang XuDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Jiayuan XuDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China.
Peng ZhangDepartment of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Wei LiDepartment of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.
Dapeng ShiDepartment of Radiology, Henan Provincial People's Hospital and Zhengzhou University People's Hospital, Zhengzhou, China.
Caihong WangDepartment of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Su LuiDepartment of Radiology, Huaxi MR Research Center, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, China.ORCID http://orcid.org/0000-0003-3541-1769
Zhihan YanDepartment of Radiology, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China.
Feng ChenDepartment of Radiology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, China.ORCID http://orcid.org/0000-0002-9129-7895
Jing ZhangDepartment of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China.
Jiance LiDepartment of Radiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wen ShenDepartment of Radiology, Tianjin First Center Hospital, Tianjin, China.
Yanwei MiaoDepartment of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China.
Dawei WangDepartment of Radiology, Qilu Hospital of Shandong University, Jinan, China.
Junfang XianDepartment of Radiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.ORCID http://orcid.org/0000-0003-2191-9393
Jia-Hong GaoCenter for MRI Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.ORCID http://orcid.org/0000-0002-9311-0297
Xiaochu ZhangDivision of Life Science and Medicine, University of Science and Technology of China, Hefei, China.ORCID http://orcid.org/0000-0002-7541-0130
Kai XuDepartment of Radiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xi-Nian ZuoDevelopmental Population Neuroscience Research Center at IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.ORCID http://orcid.org/0000-0001-9110-585X
Longjiang ZhangDepartment of Radiology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Zhaoxiang YeDepartment of Radiology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Tianjin Medical University, Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.ORCID http://orcid.org/0000-0003-3157-8393
Jingliang ChengDepartment of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. cjr.chjl@vip.163.com.ORCID http://orcid.org/0000-0001-9944-8419
Mulin Jun LiDepartment of Bioinformatics, the Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China. mulin@tmu.edu.cn.ORCID http://orcid.org/0000-0003-3598-3679
Chunshui YuDepartment of Radiology, Tianjin Key Laboratory of Functional Imaging and State Key Laboratory of Experimental Hematology, Tianjin Medical University General Hospital, Tianjin, China. chunshuiyu@tmu.edu.cn.ORCID http://orcid.org/0000-0001-5648-5199
CHIMGEN Consortium
Funding
National Natural Science Foundation of China (National Science Foundation of China) 81425013National Natural Science Foundation of China (National Science Foundation of China) 82030053
Abstract
Genome-wide association studies of brain imaging phenotypes are mainly performed in European populations, but other populations are severely under-represented. Here, we conducted Chinese-alone and cross-ancestry genome-wide association studies of 3,414 brain imaging phenotypes in 7,058 Chinese Han and 33,224 white British participants. We identified 38 new associations in Chinese-alone analyses and 486 additional new associations in cross-ancestry meta-analyses at P < 1.46 × 10
Indexed as
BrainEast Asian PeopleNeuroimagingWhite PeopleAdultChinaFemaleGenome-Wide Association StudyHumansMagnetic Resonance ImagingMalePhenotypePolymorphism, Single NucleotideUnited Kingdom
Identifiers
PMID
38811844What OpenQuestion holds
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.