Evidence map›Paper›PMID 38811794›Full record

ArticleScientific reports2024

Adverse effects of excessive dietary arachidonic acid on survival, PUFA-derived enzymatic and non-enzymatic oxylipins, stress response in rainbow trout fry.

Emilie Cardona, Emilien Segret, Cécile Heraud, Jerome Roy, Claire Vigor, Valérie Gros, Guillaume Reversat, Battitte Sancho-Zubeldia, Camille Oger, Anaelle Durbec and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Emilie CardonaViviers de Rébénacq, 64260, Rébénacq, France. emilie.cardona@inrae.fr.
Emilien SegretViviers de Sarrance, 64490, Sarrance, France.
Cécile HeraudINRAE, Univ. Pau & Pays Adour, E2S UPPA, NUMEA, 64310, Saint Pée-sur-Nivelle, France.
Jerome RoyINRAE, Univ. Pau & Pays Adour, E2S UPPA, NUMEA, 64310, Saint Pée-sur-Nivelle, France.
Claire VigorInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Valérie GrosInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Guillaume ReversatInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Battitte Sancho-ZubeldiaViviers de Sarrance, 64490, Sarrance, France.
Camille OgerInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Anaelle DurbecI2MC, Université de Toulouse, Inserm, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Justine Bertrand-MichelI2MC, Université de Toulouse, Inserm, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France.
Anne SurgetINRAE, Univ. Pau & Pays Adour, E2S UPPA, NUMEA, 64310, Saint Pée-sur-Nivelle, France.
Jean-Marie GalanoInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Geneviève CorrazeINRAE, Univ. Pau & Pays Adour, E2S UPPA, NUMEA, 64310, Saint Pée-sur-Nivelle, France.
Yoann CachelouViviers de Rébénacq, 64260, Rébénacq, France.
Yann MarchandLegouessant Aquaculture, 22402, Lamballe, France.
Thierry DurandInstitut des Biomolécules Max Mousseron (IBMM), Pôle Chimie Balard Recherche, UMR5247, CNRS, Université de Montpellier, ENSCM, 34293, Montpellier, France.
Frederic CachelouViviers de Sarrance, 64490, Sarrance, France.
Sandrine Skiba-CassyINRAE, Univ. Pau & Pays Adour, E2S UPPA, NUMEA, 64310, Saint Pée-sur-Nivelle, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arachidonic acid (C20: 4n-6, AA) plays a fundamental role in fish physiology, influencing growth, survival and stress resistance. However, imbalances in dietary AA can have detrimental effects on fish health and performance. Optimal AA requirements for rainbow trout have not been established. This study aimed to elucidate the effects of varying dietary AA levels on survival, growth, long-chain polyunsaturated fatty acid (LC-PUFA) biosynthetic capacity, oxylipin profiles, lipid peroxidation, and stress resistance of rainbow trout fry. Over a period of eight weeks, 4000 female rainbow trout fry at the resorptive stage (0.12 g) from their first feeding were fed diets with varying levels of AA (0.6%, 1.1% or 2.5% of total fatty acids) while survival and growth metrics were closely monitored. The dietary trial was followed by an acute confinement stress test. Notably, while the fatty acid profiles of the fish reflected dietary intake, those fed an AA-0.6% diet showed increased expression of elongase5, highlighting their inherent ability to produce LC-PUFAs from C18 PUFAs and suggesting potential AA or docosapentaenoic acid

Indexed as

Arachidonic AcidFatty Acids, UnsaturatedOncorhynchus mykissOxylipinsStress, PhysiologicalAnimal FeedAnimalsDietFemaleLipid PeroxidationOxidative StressArachidonic AcidFatty Acids, UnsaturatedOxylipinsArachidonic acidConfinement stressDopamineOxylipinSerotoninTrout

Identifiers

PMID38811794
PMCPMC11137042

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.