Evidence map›Paper›PMID 38811723›Full record

ArticleNature2024

Transcriptional control of the Cryptosporidium life cycle.

Katelyn A Walzer, Jayesh Tandel, Jessica H Byerly, Abigail M Daniels, Jodi A Gullicksrud, Eoin C Whelan, Stephen D Carro, Elise Krespan, Daniel P Beiting, Boris Striepen

Abstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Virulence · 2026
    Article
  2. Article
  3. Article
  4. bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Single-cell analysis ofbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. A single-cell atlas ofbioRxiv : the preprint server for biology · 2026
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Molecular biology of the cell · 2025
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katelyn A WalzerDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0003-1179-9164
Jayesh TandelDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Jessica H ByerlyDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Abigail M DanielsDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-6542-1960
Jodi A GullicksrudDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Eoin C WhelanDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Stephen D CarroDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Elise KrespanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Daniel P BeitingDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Boris StriepenDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA. striepen@upenn.edu.ORCID 0000-0002-7426-432X

Funding

Immunity to CryptosporidiumR01AI148249 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHRISTOPHER A HUNTER, BORIS STRIEPEN · 2020 to 2026
$5.3M
The role of CD40L in resistance to enteric infectionU01AI163671 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHRISTOPHER A HUNTER, BORIS STRIEPEN · 2021 to 2026
$4.7M
Genetic Analysis of CryptosporidiumR01AI112427 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI STRIEPEN, BORIS · 2014 to 2023
$4.2M
Sexual Development of CryptosporidiumR01AI127798 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI STRIEPEN, BORIS · 2017 to 2025
$4.1M
Elucidating the roles of transcriptional regulators during the Cryptosporidium life cycleF32AI154666 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI WALZER, KATELYN ANN · 2020 to 2022
$206k
NIAID NIH HHS F32 AI154666NIAID NIH HHS R01 AI112427NIAID NIH HHS R01 AI127798NIAID NIH HHS R01 AI148249NIAID NIH HHS U01 AI163671
6 · The paper itself

Abstract

The parasite Cryptosporidium is a leading agent of diarrhoeal disease in young children, and a cause and consequence of chronic malnutrition

Indexed as

CryptosporidiosisCryptosporidium parvumGene Expression RegulationLife Cycle StagesTranscription, GeneticAnimalsFemaleGene Regulatory NetworksHumansMaleMiceProto-Oncogene Proteins c-mybSex Determination ProcessesSingle-Cell Gene Expression AnalysisProto-Oncogene Proteins c-myb

Identifiers

PMID38811723
PMCPMC12057246

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.