ArticleNPJ Parkinson's disease2024
Digital outcome measures from smartwatch data relate to non-motor features of Parkinson's disease.
Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical Outcomes of Passive Sensors in Remote Monitoring: A Systematic Review.Sensors (Basel, Switzerland) · 2025Pooled it
- Movement Disorders and Smart Wrist Devices: A Comprehensive Study.Sensors (Basel, Switzerland) · 2025Pooled it
- Smartphone-Based Multimodal Digital Biomarker Integration for Parkinson's Disease Screening and Diagnostic Support.Neurology and therapy · 2026Article
- From phenotype to biology: a multi-modal roadmap of biofluid, tissue, imaging, and digital biomarkers in Parkinson's disease.Translational neurodegeneration · 2026Review
- Heart rate monitoring using wrist photoplethysmography in Parkinson disease: feasibility and relation with autonomic dysfunction.Journal of neuroengineering and rehabilitation · 2026Article
- A framework of digital biomarkers for neurodegenerative diseases.Nature reviews bioengineering · 2026Article
- Multimodal Intelligent Monitoring of Parkinson Disease: Scoping Review of Progress and Translational Challenges.Journal of medical Internet research · 2026Article
- Digital Technology for Sleep Symptoms in Parkinson's Disease: A Scoping Review.Journal of movement disorders · 2026Article
- Associations Between Daily Step Counts and Sleep Parameters in Parkinson's Disease: A Scoping Review.Sensors (Basel, Switzerland) · 2025Article
- Levodopa treatment: impacts and mechanisms throughout Parkinson's disease progression.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Modernizing the Staging of Parkinson Disease Using Digital Health Technology.Journal of medical Internet research · 2025Article
- Wearable Sensors for Sleep Monitoring in Free-Living Environments: A Scoping Review on Parkinson's Disease.Biosensors · 2025Article
- Accelerometry-derived features of physical activity, sleep and circadian rhythm relate to non-motor symptoms in individuals with isolated REM sleep behavior disorder.Journal of neurology · 2025Article
- Stage-specific digital health technology biomarkers enhance diagnostic and early progression detection in Parkinson's disease.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monitoring of Parkinson's disease (PD) has seen substantial improvement over recent years as digital sensors enable a passive and continuous collection of information in the home environment. However, the primary focus of this work has been motor symptoms, with little focus on the non-motor aspects of the disease. To address this, we combined longitudinal clinical non-motor assessment data and digital multi-sensor data from the Verily Study Watch for 149 participants from the Parkinson's Progression Monitoring Initiative (PPMI) cohort with a diagnosis of PD. We show that digitally collected physical activity and sleep measures significantly relate to clinical non-motor assessments of cognitive, autonomic, and daily living impairment. However, the poor predictive performance we observed, highlights the need for better targeted digital outcome measures to enable monitoring of non-motor symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.