SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Global quality of life and mortality risk in patients with cancer: a systematic review and meta-analysis.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Health-related quality of life domains relevant to people in Europe undergoing cancer treatment: a systematic review of qualitative research.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- Assessing the impact of neoadjuvant chemotherapy and chemoradiotherapy on quality of life during treatment in esophageal cancer: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Pooled it
- The Impact of Chronic Stress on Treatment Outcomes of Cancer Patients with Divergent Survival Rates: A Systematic Review.International journal of molecular sciences · 2026Pooled it
- Global research trends and insights in acupuncture randomized controlled trials: a bibliometric analysis.Frontiers in medicine · 2026Pooled it
- Relationship between patient-reported health-related quality of life as measured with the SF-36 or SF-12 and their mortality risk in patients with diverse cancer type: a meta-analysis.International journal of clinical oncology · 2025Pooled it
- Can patient-reported outcome measures predict mortality in neurological populations? A systematic review.Frontiers in neurologyPooled it
- Effects of a 2-Year Primary Care Weight Loss Intervention on Quality of Life in Patients With Obesity.Obesity (Silver Spring, Md.) · 2026Trial
- Group-based trajectories of health-related quality of life among pediatric patients with high-risk Hodgkin lymphoma.Journal of the National Cancer Institute · 2025Trial
- Appetite loss during chemotherapy is associated with reduced dietary intake and quality of life in patients with gynecologic cancer: a prospective observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Association between symptom experience and long-term survival in people treated for cancer.ESMO open · 2026Article
- Quality of life assessment for colorectal cancer follow-up: A latent profile analysis of EORTC measures.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Comparison of thyroid-specific quality of life after thermal ablation vs. thyroid lobectomy for benign thyroid nodules.BMC endocrine disorders · 2026Article
- Review
- Effects of trimodal prehabilitation on quality of life and negative emotions in patients with advanced triple-negative breast cancer.Frontiers in oncology · 2026Article
- Effects of exercise therapy in patients with pancreatic cancer: A systematic review and meta-analysis.International journal of nursing studies advances · 2025Review
- Article
- Bibliometric and visual analysis of cancer-related insomnia research from 2015 to 2025.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Review
- Mental Comorbidity and Psychosocial Care in Patients with Cancer.Deutsches Arzteblatt international · 2025Article
- Fatigue Level Associated with Quality of Life for Prostate Cancer Patients: Results from the All of Us Research Program.Cancers · 2025Article
- Virtual Reality and Sound Intervention under Chemotherapy (ViSu): study protocol for a three-arm randomised-controlled trial.BMJ open · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeThis systematic review and meta-analysis aimed to examine the impact of global quality of life (QOL) on mortality risk in patients with cancer, considering cancer type and timepoint of QOL assessment.
methodsA systematic search was conducted using Cumulated Index to Nursing and Allied Health Literature, PubMed/MEDLINE, and Scopus databases from inception to December 2022. Observational studies that assessed QOL and examined mortality risk in patients with cancer were extracted. Subgroup analyses were performed for cancer types and timepoints of QOL assessment.
resultsOverall, global QOL was significantly associated with mortality risk (hazard ratio: 1.06, 95% confidence interval: 1.05-1.07; p < 0.00001). A subgroup analysis based on cancer type demonstrated that lung, head and neck, breast, esophagus, colon, prostate, hematologic, liver, gynecologic, stomach, brain, bladder, bone and soft tissue, and mixed type cancers were significantly associated with mortality risk; however, melanoma and pancreatic cancer were not significantly associated with mortality risk. Additionally, global QOL was associated with mortality risk at all timepoints (pretreatment, posttreatment, and palliative phase); pretreatment QOL had the largest impact, followed by posttreatment QOL.
conclusionThese findings provide evidence that QOL is associated with mortality risk in patients with cancer at any timepoint. These results indicate the importance of evaluating the QOL and supportive interventions to improve QOL in any phase.
Indexed as
Identifiers
38811448What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.