ArticlePediatric surgery international2024
Clinical features and treatment of heterotopic pancreas in children: a multi-center retrospective study.
Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Gastric Ectopic Pancreas: A Pediatric Case Report.Cureus · 2026Article
- Enhanced recovery after surgery protocol implementation in pediatric Meckel's diverticulum resection: A clinical outcome study.World journal of gastrointestinal surgery · 2025Article
- Various Phenotypes of Ectopic Pancreatic Tissue in Children: Case Series and Literature Review.Diagnostics (Basel, Switzerland) · 2025Article
- A 13-year-old with dual pancreatic rests.JPGN reports · 2025Article
- Congenital duodenal diaphragm with heterotopic pancreas: a case report and literature review.Frontiers in pediatrics · 2025Article
- Advances in the diagnosis and treatment of heterotopic pancreas.World journal of clinical cases · 2024Article
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15 authors.
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Abstract
objectiveHeterotopic pancreas, an uncommon condition in children, can present with diagnostic and treatment challenges. This study aimed to evaluate the clinical features and treatment options for this disorder in pediatric patients.
methodsWe conducted a retrospective analysis, including patients diagnosed with heterotopic pancreas at four tertiary hospitals between January 2000 and June 2022. Patients were categorized into symptomatic and asymptomatic groups based on clinical presentation. Clinical parameters, including age at surgery, lesion size and site, surgical or endoscopic approach, pathological findings, and outcome, were statistically analyzed.
resultsThe study included 88 patients with heterotopic pancreas. Among them, 22 were symptomatic, and 41 were aged one year or younger. The heterotopic pancreas was commonly located in Meckel's diverticulum (46.59%), jejunum (20.45%), umbilicus (10.23%),ileum (7.95%), and stomach (6.82%). Sixty-six patients had concomitant diseases. Thirty-three patients had heterotopic pancreas located in the Meckel's diverticulum, with 80.49% of cases accompanied by gastric mucosa heterotopia (GMH). Patients without accompanying GMH had a higher prevalence of heterotopic pancreas-related symptoms (75%). Treatment modalities included removal of the lesions by open surgery, laparoscopic or laparoscopic assisted surgery, or endoscopic surgery based on patient's age, the lesion site and size, and coexisting diseases.
conclusionsOnly one-fourth of the patients with heterotopic pancreas presented with symptoms. Those located in the Meckel's diverticulum have commonly accompanying GMH. Open surgical, laparoscopic surgical or endoscopic resection of the heterotopic pancreas is recommended due to potential complications. Future prospective multicenter studies are warranted to establish rational treatment options.
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