Evidence map›Paper›PMID 38811407›Full record

ReviewAnalytical and bioanalytical chemistry2024

Forty years of advances in optical biosensors-are "autonomous" biosensors in our future?

Frances S Ligler, George T Ligler

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Frances S LiglerDepartment of Biomedical Engineering, Texas A&M University, College Station, TX, USA. fsligler@tamu.edu.ORCID http://orcid.org/0000-0003-4909-2084
George T LiglerDepartment of Multidisciplinary Engineering, Texas A&M University, College Station, TX, USA.ORCID http://orcid.org/0009-0005-5501-157X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical biosensors have employed at least three distinct system architectures over the last 40 years, moving from "sample in-answer out" systems to completely embedding the optical biosensor into the sample to embedding the recognition module in the sample and optically interrogating the recognition module from outside of the sample. This trends article provides an overview of the evolution of these three system architectures and discusses how each architecture has been applied to solve the measurement challenges of a wide variety of applications. A fourth biosensor system architecture, that of an "autonomous" biosensor which "takes the user out of the loop" while both detecting target analytes and responding to that measurement, is currently under development for applications initially including environmental cleanup and "smart therapeutics." As is the case in many other areas of technology, it will be profoundly interesting to observe the further development and application of elegant, simpler (optical) biosensor systems to address tomorrow's measurement needs.

Indexed as

Biosensing TechniquesHumansOptical DevicesOptics and PhotonicsAutonomous biosensorsEmbedded sensorsOptical biosensorsSmart tattoo

Identifiers

PMID38811407
PMCPMC11584417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.